Protein Alignment moody and BDKRB1

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_000701.2
• Gene: BDKRB1 / 623
• HGNCID: 1029
• Length: 353
• Species: Homo sapiens
• Alignment Length: 402
• Identity: 82/402 - (20%)
• Similarity: 152/402 - (37%)
• Gaps: 92/402 - (22%)

  Fly     9 LEDGYPPLEALT---TMVPPADATGFSQSL----LTFAAVMTFLIMI--VGICGNLLTVVALLKC 64
            :...:||||..:   :.:.|.:||....:.    |....:.||:|.|  .|:.|||..::..|..
Human     1 MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLLVFLLP 65

  Fly    65 PKVRNVAAAFIISLCIADLLFCALVLPFQGLR-FVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIA 128
            .:..|||..::.:|..:||:| .|.|||.... :.|..|..|.:|||:|..:...|:.:|:..:.
Human    66 RRQLNVAEIYLANLAASDLVF-VLGLPFWAENIWNQFNWPFGALLCRVINGVIKANLFISIFLVV 129

  Fly   129 MITINRYVMITHHGLYARIYKRHWIAVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTD 193
            .|:.:||.::.|.....|..:|....|.....|:....:.:||.|....:...|..:..|.::..
Human   130 AISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQAVPDLNITACILLLP 194

  Fly   194 DHG-HSSK-TTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSG 256
            ... |.:: ..|.|..|::|...|      :|:..|               |..:||
Human   195 HEAWHFARIVELNILGFLLPLAAI------VFFNYH---------------ILASLR-------- 230

  Fly   257 ALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLS 321
                                                 ||.:..|.....|.:.:.|.::|.:.::
Human   231 -------------------------------------TREEVSRTRCGGRKDSKTTALILTLVVA 258

  Fly   322 FVVCYLPITIVKVADKNVEHPSLHICSY------------ILLYLSACINPIIYVIMNKQYR-KA 373
            |:||:.|.......:...:..::..|.:            ...:.::.:||:|||.:.:.:| |.
Human   259 FLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFFAFTNSSLNPVIYVFVGRLFRTKV 323

  Fly   374 YKTVVFCQPARL 385
            ::....|.|..|
Human   324 WELYKQCTPKSL 335

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	71/354 (20%)
		TM helix 1	38..64	CDD:320338	9/27 (33%)
		TM helix 2	71..94	CDD:320338	9/22 (41%)
		TM helix 3	109..139	CDD:320338	8/29 (28%)
		TM helix 4	153..171	CDD:320338	2/17 (12%)
		TM helix 5	196..305	CDD:320338	14/110 (13%)
		TM helix 6	306..336	CDD:320338	7/29 (24%)
		TM helix 7	342..367	CDD:320338	6/36 (17%)
BDKRB1	NP_000701.2	7tmA_BK-1	38..323	CDD:320502	70/351 (20%)
		TM helix 1	39..65	CDD:320502	9/25 (36%)
		TM helix 2	72..97	CDD:320502	9/25 (36%)
		TM helix 3	110..140	CDD:320502	8/29 (28%)
		TM helix 4	153..174	CDD:320502	4/20 (20%)
		TM helix 5	199..228	CDD:320502	9/49 (18%)
		TM helix 6	243..273	CDD:320502	7/29 (24%)
		TM helix 7	291..316	CDD:320502	5/24 (21%)