Protein Alignment moody and NPY5R

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: XP_011530317.1
• Gene: NPY5R / 4889
• HGNCID: 7958
• Length: 452
• Species: Homo sapiens
• Alignment Length: 428
• Identity: 103/428 - (24%)
• Similarity: 169/428 - (39%)
• Gaps: 98/428 - (22%)

  Fly    27 DATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLP 91
            |...|...|.||       :.::|..||||.::||:|....:......|.:|..:|:|......|
Human    46 DLQYFLIGLYTF-------VSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSP 103

  Fly    92 FQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITH---------HGLYARI 147
            |.....:...|..|:|:|.::||:|..::.||.|.:..|.|.||.||.|         ||.:
Human   104 FTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYF--- 165

  Fly   148 YKRHWIAVMIAACWLFSYGMQLP-----TLLGEWGRFG---YDSR-LQTCSIMTDDHGHSSKTTL 203
                    :||..|...:.:..|     :|:.....||   ..|| |...|..:|.:..:...:|
Human   166 --------LIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISL 222

  Fly   204 FITAFVIP--CLVI--------IAC-----------YAKIFWVVHKSEQR--------------- 232
            .:..:::|  ||.:        |:|           ...|...:|.|::.
Human   223 LLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYS 287

  Fly   233 -LKRHATKQNS-----IPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQ 291
             :|:|..:.:.     :|...||.....|..||   |...|.|....|||.|   :|......:.
Human   288 FIKKHRRRYSKKTACVLPAPERPSQENHSRILP---ENFGSVRSQLSSSSKF---IPGVPTCFEI 346

  Fly   292 QPTRVKDQREVRAKRNEWRITKMVLAIF-------LSFVVCYLPITIVKVA---DKNV---EHPS 343
            :|....|..|:|.||:..||.|...::|       |.|.|.::|:.:..|.   :.|:   .|..
Human   347 KPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFK 411

  Fly   344 LHIC-SYILLYLSACINPIIYVIMNKQYRKAYKTVVFC 380
            |..| .::|..:|.|:|||:|..:|...:....:::.|
Human   412 LVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHC 449

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	99/410 (24%)
		TM helix 1	38..64	CDD:320338	8/25 (32%)
		TM helix 2	71..94	CDD:320338	6/22 (27%)
		TM helix 3	109..139	CDD:320338	12/29 (41%)
		TM helix 4	153..171	CDD:320338	4/22 (18%)
		TM helix 5	196..305	CDD:320338	29/150 (19%)
		TM helix 6	306..336	CDD:320338	10/39 (26%)
		TM helix 7	342..367	CDD:320338	9/25 (36%)
NPY5R	XP_011530317.1	7tmA_NPY5R	49..443	CDD:320520	101/417 (24%)
		TM helix 1	50..76	CDD:320520	11/32 (34%)
		TM helix 2	83..108	CDD:320520	6/24 (25%)
		TM helix 3	121..151	CDD:320520	12/29 (41%)
		TM helix 4	162..183	CDD:320520	6/31 (19%)
		TM helix 5	215..244	CDD:320520	4/28 (14%)
		TM helix 6	368..398	CDD:320520	7/29 (24%)
		TM helix 7	411..436	CDD:320520	9/24 (38%)