Protein Alignment moody and NPY1R

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_000900.1
• Gene: NPY1R / 4886
• HGNCID: 7956
• Length: 384
• Species: Homo sapiens
• Alignment Length: 447
• Identity: 107/447 - (23%)
• Similarity: 175/447 - (39%)
• Gaps: 145/447 - (32%)

  Fly    10 EDGYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAF 74
            :|.:.||..:.|:.            |.:.||     :|:|:.|||..::.:||..::|||....
Human    31 DDCHLPLAMIFTLA------------LAYGAV-----IILGVSGNLALIIIILKQKEMRNVTNIL 78

  Fly    75 IISLCIADLLFCALVLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMIT 139
            |::|..:|||...:.|||..:..:...|..|:.:|:|.||:|..:|.||:..:.:|.:.|:.:|
Human    79 IVNLSFSDLLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLI- 142

  Fly   140 HHGLYARIYKRHW------IAVMIAACWLFSYGMQLPTLLGEWGRFGY----DSRLQTCSI---- 190
                   |..|.|      ..|.||..|:.:....||.|:       |    |...|..::
Human   143 -------INPRGWRPNNRHAYVGIAVIWVLAVASSLPFLI-------YQVMTDEPFQNVTLDAYK 193

  Fly   191 ---------MTDDHGHSSKTTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNN 246
                     .:|.|..|..|.|.:..:..|...|..||.||:       .||||    :|::.:.
Human   194 DKYVCFDQFPSDSHRLSYTTLLLVLQYFGPLCFIFICYFKIY-------IRLKR----RNNMMDK 247

  Fly   247 LRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRI 311
            :|                  .|:..|..:.                                 ||
Human   248 MR------------------DNKYRSSETK---------------------------------RI 261

  Fly   312 TKMVLAIFLSFVVCYLPITIVK-VADKNVEHPSLHICSYILLYL--------SACINPIIYVIMN 367
            ..|:|:|.::|.||:||:||.. |.|.|  |..:..|::.||:|        |.|:|||.|..:|
Human   262 NIMLLSIVVAFAVCWLPLTIFNTVFDWN--HQIIATCNHNLLFLLCHLTAMISTCVNPIFYGFLN 324

  Fly   368 KQYRKAYKTVV-FCQPARLLLPFGKTNGASSAAEKWKDTGLSNNH---SRTIVSQMS 420
            |.:::..:... ||.             ..|..:.::...:|..|   |:|.:.|.|
Human   325 KNFQRDLQFFFNFCD-------------FRSRDDDYETIAMSTMHTDVSKTSLKQAS 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	93/368 (25%)
		TM helix 1	38..64	CDD:320338	8/25 (32%)
		TM helix 2	71..94	CDD:320338	8/22 (36%)
		TM helix 3	109..139	CDD:320338	10/29 (34%)
		TM helix 4	153..171	CDD:320338	5/17 (29%)
		TM helix 5	196..305	CDD:320338	17/108 (16%)
		TM helix 6	306..336	CDD:320338	13/30 (43%)
		TM helix 7	342..367	CDD:320338	10/32 (31%)
NPY1R	NP_000900.1	7tmA_NPY1R	41..331	CDD:320517	95/385 (25%)
		TM helix 1	42..68	CDD:320517	10/42 (24%)
		TM helix 2	75..100	CDD:320517	8/24 (33%)
		TM helix 3	113..143	CDD:320517	11/37 (30%)
		TM helix 4	154..175	CDD:320517	6/20 (30%)
		TM helix 5	208..237	CDD:320517	9/35 (26%)
		TM helix 6	256..286	CDD:320517	12/62 (19%)
		TM helix 7	299..324	CDD:320517	9/24 (38%)