Protein Alignment moody and MTNR1B

DIOPT Version :9

• Sequence 1: NP_001188534.1
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_005950.1
• Gene: MTNR1B / 4544
• HGNCID: 7464
• Length: 362
• Species: Homo sapiens
• Alignment Length: 363
• Identity: 84/363 - (23%)
• Similarity: 149/363 - (41%)
• Gaps: 83/363 - (22%)

  Fly    24 PPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCAL 88
            ||..|...|..|:...|        |.:.||||.::::|:..|:||....|::||.:|||:....
Human    36 PPWVAPALSAVLIVTTA--------VDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFY 92

  Fly    89 VLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHHGLYARIYKRHWI 153
            ..|...:......|..|:..|:...|:...::..|:..|..|.||||..|.|...|.|||:|...
Human    93 PYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHT 157

  Fly   154 AVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCS-IMTDDHGHSSKTTLFITAFVIPCLVIIA 217
            .:.|...||.:....||...  .|...||.|:.:|: |.|....:::  .:.:..|::|..|:..
Human   158 PLHICLIWLLTVVALLPNFF--VGSLEYDPRIYSCTFIQTASTQYTA--AVVVIHFLLPIAVVSF 218

  Fly   218 CYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDV 282
            ||.:| ||:                              .|.:..:.:|.:|:.
Human   219 CYLRI-WVL------------------------------VLQARRKAKPESRLC----------- 241

  Fly   283 PETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVA------DKNVEH 341
                                 .|.::.|....:..:|:.|.:|:.|:..:.:|      :...:.
Human   242 ---------------------LKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQI 285

  Fly   342 P-SLHICSYILLYLSACINPIIYVIMNKQYRKAYKTVV 378
            | .|.:.||:|.|.::|:|.|:|.::|:.:|:.||.::
Human   286 PEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRIL 323

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	37/122 (30%)
		7tm_1	53..363	CDD:278431	72/317 (23%)
		7tm_4	<310..380	CDD:304433	20/76 (26%)
MTNR1B	NP_005950.1	7tm_4	48..>192	CDD:304433	45/153 (29%)
		7tm_1	57..308	CDD:278431	72/317 (23%)
		7tm_4	<131..>261	CDD:304433	39/196 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	126	1.000	Domainoid score	I5405
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4405
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4597
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.090