Protein Alignment moody and Gpr25

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_001385523.1
• Gene: Gpr25 / 363993
• RGDID: 1311611
• Length: 359
• Species: Rattus norvegicus
• Alignment Length: 408
• Identity: 82/408 - (20%)
• Similarity: 147/408 - (36%)
• Gaps: 110/408 - (26%)

  Fly    25 PADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALV 89
            ||....:|.::::...:..|   :||:.||...|..|.:..:.|.:...|::.|..|||.| .|.
  Rat    32 PAWELPYSHAIISALYLAAF---VVGLTGNTFVVWLLSRRRRPRRLVDTFVLHLAAADLGF-VLT 92

  Fly    90 LPFQGLRFVQ-GTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHHGLYAR-IYKRHW 152
            ||...:...: |.|..|..||::..|..........|.:|.::::||:.: ...|.|| :.....
  Rat    93 LPLWAVAEARGGLWPFGDGLCKISSFALAATRCAGALLLAGMSVDRYLAV-GRPLNARPLRSARC 156

  Fly   153 IAVMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTDDHGHSSKTTLFITAFVIPCLVIIA 217
            :....:|.|..::...|||||....:...|.....|:....|........|.:..|.:|..|.:.
  Rat   157 VRASCSAVWAAAFLAGLPTLLYRRLQPSLDGEGSQCAEEPSDALQGVGLLLLLLTFALPLAVTLT 221

  Fly   218 CYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDV 282
            ||    |.|.:...|::
  Rat   222 CY----WRVSRRLLRVR------------------------------------------------ 234

  Fly   283 PETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADKNVEHPSLHI- 346
                                ||:.|..||...|.::   ||..:||.:|::.........:|.:
  Rat   235 --------------------RARGNSLRIIFTVESV---FVGSWLPFSILRALFYLARLRALPLP 276

  Fly   347 CSYI------------LLYLSACINPIIYVIMNKQYRKAYK----TVVFCQPARL---------- 385
            ||.:            |.::.:|.||:||:::::.:|...:    |.|..|..|:
  Rat   277 CSLLLALRWGLTVATCLAFVHSCANPVIYLLLDRSFRARVRFGPCTRVGRQVRRISSASSLSRDD 341

  Fly   386 -LLPFGKTNGASSAAEKW 402
             .:.:|:::.|:||...|
  Rat   342 SSVFWGRSSKANSALAAW 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	70/351 (20%)
		TM helix 1	38..64	CDD:320338	7/25 (28%)
		TM helix 2	71..94	CDD:320338	9/22 (41%)
		TM helix 3	109..139	CDD:320338	6/29 (21%)
		TM helix 4	153..171	CDD:320338	3/17 (18%)
		TM helix 5	196..305	CDD:320338	10/108 (9%)
		TM helix 6	306..336	CDD:320338	9/29 (31%)
		TM helix 7	342..367	CDD:320338	9/37 (24%)
Gpr25	NP_001385523.1	7tm_GPCRs	42..315	CDD:475119	70/352 (20%)
		TM helix 1	43..67	CDD:410628	7/26 (27%)
		TM helix 2	76..97	CDD:410628	9/21 (43%)
		TM helix 3	114..136	CDD:410628	3/21 (14%)
		TM helix 4	159..175	CDD:410628	3/15 (20%)
		TM helix 5	201..223	CDD:410628	4/21 (19%)
		TM helix 6	241..263	CDD:410628	8/24 (33%)
		TM helix 7	284..309	CDD:410628	6/24 (25%)