Protein Alignment moody and GPR25

DIOPT Version :9

• Sequence 1: NP_001188534.1
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_005289.2
• Gene: GPR25 / 2848
• HGNCID: 4480
• Length: 361
• Species: Homo sapiens
• Alignment Length: 390
• Identity: 85/390 - (21%)
• Similarity: 142/390 - (36%)
• Gaps: 125/390 - (32%)

  Fly    11 DGYPPLEALTTMVPPADAT-GFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAF 74
            ||...||    :.|..|.. |:     .:...:......||:.||...|..|......|.:...|
Human    22 DGLEELE----LCPAGDLPYGY-----VYIPALYLAAFAVGLLGNAFVVWLLAGRRGPRRLVDTF 77

  Fly    75 IISLCIADLLFCALVLP-FQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMI 138
            ::.|..|||.| .|.|| :.....:.|.|..|..||:|..|...|......|.:|.::::||:.:
Human    78 VLHLAAADLGF-VLTLPLWAAAAALGGRWPFGDGLCKLSSFALAGTRCAGALLLAGMSVDRYLAV 141

  Fly   139 THHGLYARIYKRHWIAVMIAAC---WLFSYGMQLPTLL--------GEWGRFGYDSRLQTCSIMT 192
            ... |.||..:....|  :|:|   |..:....||:|:        |     |.||:   |.
Human   142 VKL-LEARPLRTPRCA--LASCCGVWAVALLAGLPSLVYRGLQPLPG-----GQDSQ---CG--- 192

  Fly   193 DDHGHSSK---TTLFITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTG 254
            ::..|:.:   ..|.:..||:|.:|.:.||.:|       .:||:|
Human   193 EEPSHAFQGLSLLLLLLTFVLPLVVTLFCYCRI-------SRRLRR------------------- 231

  Fly   255 SGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIF 319
                                                  |..|.     ||:||..||   :.||.
Human   232 --------------------------------------PPHVG-----RARRNSLRI---IFAIE 250

  Fly   320 LSFVVCYLPITIVKVADKNVEHPSLHICSYILL-------------YLSACINPIIYVIMNKQYR 371
            .:||..:||.:.::.........:|.:...:||             ::::|.||:||:::::.:|
Human   251 STFVGSWLPFSALRAVFHLARLGALPLPCPLLLALRWGLTIATCLAFVNSCANPLIYLLLDRSFR 315

  Fly   372  371
            Human   316  315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	35/126 (28%)
		7tm_1	53..363	CDD:278431	73/337 (22%)
		7tm_4	<310..380	CDD:304433	17/75 (23%)
GPR25	NP_005289.2	7tm_1	56..307	CDD:278431	73/337 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100