Protein Alignment moody and GPR15

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_005281.1
• Gene: GPR15 / 2838
• HGNCID: 4469
• Length: 360
• Species: Homo sapiens
• Alignment Length: 396
• Identity: 88/396 - (22%)
• Similarity: 141/396 - (35%)
• Gaps: 116/396 - (29%)

  Fly    38 FAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAAAFIISLCIADLLFCALVLPFQGLRFVQGTW 102
            |..|....:.:.|:.|||:.:.||...|..|.:...|||:|..:|.:|...:..:.......|.|
Human    35 FLPVFYTAVFLTGVLGNLVLMGALHFKPGSRRLIDIFIINLAASDFIFLVTLPLWVDKEASLGLW 99

  Fly   103 RHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYVMITHHGLYARIYKRHWIAVMIAACWLFSYGM 167
            |.|..||:...::...|:..|:|.:..::::||:.|....:..:..:.....|:.|:.|..|..:
Human   100 RTGSFLCKGSSYMISVNMHCSVLLLTCMSVDRYLAIVWPVVSRKFRRTDCAYVVCASIWFISCLL 164

  Fly   168 QLPTLLGEWGRFGYDSRLQTCSIMTDDHGH--SSKTT---------LFITAFVIPCLVIIACYAK 221
            .|||||         ||..|   :.||..:  ..|.|         ..|..|.:|.|.|:.||..
Human   165 GLPTLL---------SRELT---LIDDKPYCAEKKATPIKLIWSLVALIFTFFVPLLSIVTCYCC 217

  Fly   222 IFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETA 286
            |       .::|..|..:
Human   218 I-------ARKLCAHYQQ----------------------------------------------- 228

  Fly   287 PSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVK----VADKNVEH--PSLH 345
             |||......|.             .|::..:..:|:|.:||....|    |:....||  ||..
Human   229 -SGKHNKKLKKS-------------IKIIFIVVAAFLVSWLPFNTFKFLAIVSGLRQEHYLPSAI 279

  Fly   346 I-----CSYILLYLSACINPIIYVIMNKQYRKAYKTVVFCQPARLLLPFGKTNGASSAAEKWKDT 405
            :     .|..|.:.::|:||.||.|.:...|:|   :|.|     |.|..|.....|:.|
Human   280 LQLGMEVSGPLAFANSCVNPFIYYIFDSYIRRA---IVHC-----LCPCLKNYDFGSSTE----- 331

  Fly   406 GLSNNH 411
             .|::|
Human   332 -TSDSH 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	78/357 (22%)
		TM helix 1	38..64	CDD:320338	8/25 (32%)
		TM helix 2	71..94	CDD:320338	6/22 (27%)
		TM helix 3	109..139	CDD:320338	6/29 (21%)
		TM helix 4	153..171	CDD:320338	5/17 (29%)
		TM helix 5	196..305	CDD:320338	16/119 (13%)
		TM helix 6	306..336	CDD:320338	7/33 (21%)
		TM helix 7	342..367	CDD:320338	10/29 (34%)
GPR15	NP_005281.1	7tmA_GPR15	34..313	CDD:320322	79/360 (22%)
		TM helix 1	35..61	CDD:320322	8/25 (32%)
		TM helix 2	68..93	CDD:320322	6/24 (25%)
		TM helix 3	106..136	CDD:320322	6/29 (21%)
		TM helix 4	150..168	CDD:320322	5/17 (29%)
		TM helix 5	192..221	CDD:320322	8/35 (23%)
		TM helix 6	234..264	CDD:320322	7/42 (17%)
		TM helix 7	281..306	CDD:320322	8/24 (33%)