DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment moody and Agtr2

DIOPT Version :9

Sequence 1:	NP_001188534.1	Gene:	moody / 31168	FlyBaseID:	FBgn0025631	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_036626.1	Gene:	Agtr2 / 24182	RGDID:	2072	Length:	363	Species:	Rattus norvegicus

Alignment Length:	401	Identity:	84/401 - (20%)
Similarity:	153/401 - (38%)	Gaps:	124/401 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LTTMVP--PADATGFSQSL-----------LTFAAVMTFLIMIVGICGNLLTVVALLKCPK-VRN 69
            :|:.:|  ..:|||.::|.           |....|:.::|.::|...|:: ||:|..|.| .:.
  Rat    14 ITSSLPFDNLNATGTNESAFNCSHKPADKHLEAIPVLYYMIFVIGFAVNIV-VVSLFCCQKGPKK 77

  Fly    70 VAAAFIISLCIADLLFCALVLP----FQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMI 130
            |::.:|.:|.:||||..| .||    :...|:   .|..|.|:|::.......|:..|:..|..:
  Rat    78 VSSIYIFNLAVADLLLLA-TLPLWATYYSYRY---DWLFGPVMCKVFGSFLTLNMFASIFFITCM 138

  Fly   131 TINRYVMITHHGLYARIYKRHWIA-VMIAACWLFSYGMQLPTLLGEWGRFGYDSR------LQTC 188
            :::||..:.:..|..|  :..|.| .::...|..:....|||.      :..|.|      :..|
  Rat   139 SVDRYQSVIYPFLSQR--RNPWQASYVVPLVWCMACLSSLPTF------YFRDVRTIEYLGVNAC 195

  Fly   189 SIMTDDHGH---SSKTTLF--ITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLR 248
            .:......:   |:...|.  |..|:||.:.|..||..|           ::|..|.||.
  Rat   196 IMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGI-----------RKHLLKTNSY----- 244

  Fly   249 PLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITK 313
                                                    ||.:.||  ||           :.|
  Rat   245 ----------------------------------------GKNRITR--DQ-----------VLK 256

  Fly   314 MVLAIFLSFVVCYLPITIVKVADKNVEHPSLHICSYI------------LLYLSACINPIIYVIM 366
            |..|:.|:|::|:||..::...|.......::.|..|            |.:.::|:||.:|..:
  Rat   257 MAAAVVLAFIICWLPFHVLTFLDALTWMGIINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFV 321

  Fly   367 NKQYRKAYKTV 377
            ..::::..::|
  Rat   322 GNRFQQKLRSV 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	33/128 (26%)
		7tm_1	53..363	CDD:278431	72/338 (21%)
		7tm_4	<310..380	CDD:304433	17/80 (21%)
Agtr2	NP_036626.1	7tm_1	62..318	CDD:278431	72/337 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100