DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment moody and npr-31

DIOPT Version :9

Sequence 1:	NP_001188534.1	Gene:	moody / 31168	FlyBaseID:	FBgn0025631	Length:	670	Species:	Drosophila melanogaster
Sequence 2:	NP_495481.2	Gene:	npr-31 / 188235	WormBaseID:	WBGene00020319	Length:	408	Species:	Caenorhabditis elegans

Alignment Length:	461	Identity:	79/461 - (17%)
Similarity:	164/461 - (35%)	Gaps:	143/461 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 FAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAA---------AFIISLCIADLLFCALVLPFQ 93
            ||..:....::.|:.||:..|.::.:..|.:::.:         |:|..|.:.||.....:|
Worm     6 FAGFLYIATVLTGLFGNIWVVCSVARSRKPKSLMSRSSPSDRLRAYISVLAVIDLTVLMALL--- 67

  Fly    94 GLRFVQGTWRHGQV---LCRLIPFIQYGNIGV-SLLCIAMITINRYVMITHHGLYARIYKRHWIA 154
             :|.:.....|..:   .||.: |:...::.: ||..::.|:|.||:.|...  :....:|.::.
Worm    68 -VRALYHFLPHFMLDSNSCRAM-FVLENSVKITSLTVLSCISIERYITIRKP--FCSEVRRQFVN 128

  Fly   155 VMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTDDHGHS----------SKTTLFIT--A 207
            .......:| .|:.:..::           :|..|:.....|.:          .:...::|  |
Worm   129 ATPIGASIF-VGLVVGAII-----------VQINSVTVSSDGLNCVRSYRGKAIPRVASYLTAVA 181

  Fly   208 FVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGALPSGAECQPSNRVSS 272
            |::...:|...|::|.       :.::|..||:.                    |..|.::||
Worm   182 FLVDLTIISLNYSQIV-------RHVRRKFTKRR--------------------ARVQANSRV-- 217

  Fly   273 DSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSFVVCYLPITIVKVADK 337
                               :.:.|.:.|.:|      .:|..::.:.:..|||:||:::::....
Worm   218 -------------------RESLVNEPRYMR------EMTAAIVRVGVFHVVCWLPMSLMQFIPD 257

  Fly   338 NVEHPSL-------------HICSYI------LLYLSACINPIIYVIMNKQYRKAYKTVVFCQPA 383
            |.....|             .|..::      |..::|..:.|.|.:||:..|...:   |....
Worm   258 NTIQSELTAGIRLFSNFRDYSITRWLIFIATWLTSMNAAGDWIFYAVMNRDLRNLIR---FATER 319

  Fly   384 RLLLPFGKTNGASSAAEKWKDTGLSNN--------HSRTIVSQMSGGTGAASGAGTATGTAAVAV 440
            |      |.:..|.||....:..|...        ||.:..|.:.|....|:||         :.
Worm   320 R------KRSTMSHAASPSTNRSLRQQVPPSMKVLHSISYRSSIGGSMDDAAGA---------SF 369

  Fly   441 MQTPPE 446
            :|:.|:
Worm   370 LQSSPK 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	25/135 (19%)
		7tm_1	53..363	CDD:278431	56/353 (16%)
		7tm_4	<310..380	CDD:304433	16/88 (18%)
npr-31	NP_495481.2	7tm_classA_rhodopsin-like	9..306	CDD:381740	58/369 (16%)
		TM helix 1	9..31	CDD:381740	4/21 (19%)
		TM helix 2	40..70	CDD:381740	6/33 (18%)
		TM helix 3	86..108	CDD:381740	5/22 (23%)
		TM helix 4	131..145	CDD:381740	2/14 (14%)
		TM helix 5	171..194	CDD:381740	4/22 (18%)
		TM helix 6	225..254	CDD:381740	8/34 (24%)
		TM helix 7	281..306	CDD:381740	4/24 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100