Protein Alignment moody and npr-25

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_505883.1
• Gene: npr-25 / 179570
• WormBaseID: WBGene00011381
• Length: 376
• Species: Caenorhabditis elegans
• Alignment Length: 454
• Identity: 93/454 - (20%)
• Similarity: 170/454 - (37%)
• Gaps: 132/454 - (29%)

  Fly    12 GYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIVGICGN--LLTVVALLKCPKVRNVAA-- 72
            ||||        ||.....|:::.:.::....|     |..||  :|:.|..:......:|.|
 Worm     9 GYPP--------PPLVGASFAKTAIPYSICFVF-----GTLGNTAVLSYVFFITRSLKSSVTALG 60

  Fly    73 ---AFIISLCIADLLFCALVLPFQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINR 134
               .:|::||..||| ..:.:||.....:...|..|:::|::...::..|...|...:..:..:|
 Worm    61 NTFIYIVALCAVDLL-VTVSIPFSLSYMILNNWVFGELVCKIHFMLELSNKMCSTFILTALAFDR 124

  Fly   135 YVMITHHGLYARIYK-RH--WIAVMIAACWLFSYGMQLPTLL---------GEWGRFGYDSRLQT 187
            |:.|.|..: .||:: ||  :|..::|...||   :..|.:|         |::.....:.|.:.
 Worm   125 YMAICHPEI-KRIHEMRHTIYITTILATLSLF---LISPVVLSARVTSFKSGQYFVSAKNERHEV 185

  Fly   188 CSIMTDDHGHSSKTTLFITAFVI------PCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNN 246
            ...|..| |.:.:..::::||:|      ||.::...||||.       .||:|
 Worm   186 IRQMCID-GMALEWKVWVSAFLIFFAFLLPCTLLTYFYAKIV-------LRLRR----------- 231

  Fly   247 LRPLASTGSGALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRI 311
                                                        |:.|.::.:..:|      ||
 Worm   232 --------------------------------------------QRRTMLQSRIPLR------RI 246

  Fly   312 TKMVLAIFLSFVVCYLPITIVKVAD---------KNVEHPSLHICSYILLYLSACINPIIYVIMN 367
            |...:|....::.|::|..:.::.:         .|.:..:....|::|.::||..|.|.|..:|
 Worm   247 TIYTMAATFFYLSCHIPFWLPQIYNIFSTVLGHKMNPKVMTFTYYSHLLPFISAAFNWIFYARLN 311

  Fly   368 KQYRKAYKTVVFCQPARLLLPFGKT---NGASSAA----EKWKDTGLSNNHSRTIVSQMSGGTG 424
            .|::|....|.    .|::....|:   .|.|.||    .|:.|..|...|....:|..|...|
 Worm   312 SQFKKGLVLVT----ERMIRKRTKSMHEKGYSEAAVELTSKFDDVPLMCPHCEAQLSIRSSSNG 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	72/370 (19%)
		TM helix 1	38..64	CDD:320338	6/27 (22%)
		TM helix 2	71..94	CDD:320338	9/27 (33%)
		TM helix 3	109..139	CDD:320338	5/29 (17%)
		TM helix 4	153..171	CDD:320338	4/17 (24%)
		TM helix 5	196..305	CDD:320338	16/114 (14%)
		TM helix 6	306..336	CDD:320338	6/29 (21%)
		TM helix 7	342..367	CDD:320338	7/24 (29%)
npr-25	NP_505883.1	7tm_classA_rhodopsin-like	24..311	CDD:410626	69/365 (19%)
		TM helix 1	24..49	CDD:410626	6/29 (21%)
		TM helix 2	62..87	CDD:410626	8/25 (32%)
		TM helix 3	99..129	CDD:410626	5/29 (17%)
		TM helix 4	141..160	CDD:410626	5/21 (24%)
		TM helix 5	199..224	CDD:410626	6/24 (25%)
		TM helix 6	244..271	CDD:410626	7/32 (22%)
		TM helix 7	286..311	CDD:410626	7/24 (29%)