Protein Alignment moody and Agtr1b

DIOPT Version :10

• Sequence 1: NP_569970.2
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_780295.2
• Gene: Agtr1b / 11608
• MGIID: 87965
• Length: 359
• Species: Mus musculus
• Alignment Length: 427
• Identity: 86/427 - (20%)
• Similarity: 162/427 - (37%)
• Gaps: 114/427 - (26%)

  Fly     8 SLEDGYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIVGICGNLLTVVALLKCPKVRNVAA 72
            |:|||   ::.:....|.|   |....:......:..:|.:|||.||.|.|:.:....|::.||:
Mouse     6 SIEDG---IKRIQDDCPKA---GRHNYIFVMIPTLYSIIFVVGIFGNSLVVIVIYFYMKLKTVAS 64

  Fly    73 AFIISLCIADLLFCALVLPFQGL-RFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMITINRYV 136
            .|:::|.:|||.| .|.||...: ..::..|..|..||::.......|:..|:..:..::|:||:
Mouse    65 VFLLNLALADLCF-LLTLPLWAVYTAMEYQWPFGNHLCKIASASVSFNLYASVFLLTCLSIDRYL 128

  Fly   137 MITHHGLYARIYKRHWIA-VMIAACWLFSYGMQLPTLLGEWGRFGYDSRLQTCSIMTDDHGHSSK 200
            .|. |.:.:|:.:...:| |.....||.:....||.::.....|..::.:..|:.    |..|..
Mouse   129 AIV-HPMKSRLRRTMLVAKVTCIIIWLMAGLASLPAVIHRNVYFIENTNITVCAF----HYESQN 188

  Fly   201 TTL--------FITAFVIPCLVIIACYAKIFWVVHKSEQRLKRHATKQNSIPNNLRPLASTGSGA 257
            :||        .|..||.|.::|:..|. :.|      :.||:....|.:.|.|
Mouse   189 STLPIGLGLTKNILGFVFPFVIILTSYT-LIW------KALKKAYKIQKNTPRN----------- 235

  Fly   258 LPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQPTRVKDQREVRAKRNEWRITKMVLAIFLSF 322
                                                    |.           |.::::||.|.|
Mouse   236 ----------------------------------------DD-----------IFRIIMAIVLFF 249

  Fly   323 VVCYLPITIVKVADKNVEHPSLHIC------------SYILLYLSACINPIIYVIMNKQYRKAYK 375
            ...::|..|....|..::...:|.|            :..:.|.:.|:||:.|..:.|::::.:.
Mouse   250 FFSWVPHQIFSFLDVLIQLGVIHDCEIADVVDTAMPITICIAYFNNCLNPLFYGFLGKKFKRYFL 314

  Fly   376 TVVFCQPARL-----------LLPFGKTNGASSAAEK 401
            .::...|.:.           .|.:..::..||:|.|
Mouse   315 QLLKYIPPKARSHAGLSTKMSTLSYRPSDNMSSSARK 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_569970.2	7tmA_GPR84-like	37..374	CDD:320338	73/358 (20%)
		TM helix 1	38..64	CDD:320338	8/25 (32%)
		TM helix 2	71..94	CDD:320338	10/22 (45%)
		TM helix 3	109..139	CDD:320338	6/29 (21%)
		TM helix 4	153..171	CDD:320338	5/18 (28%)
		TM helix 5	196..305	CDD:320338	16/116 (14%)
		TM helix 6	306..336	CDD:320338	7/29 (24%)
		TM helix 7	342..367	CDD:320338	7/36 (19%)
Agtr1b	NP_780295.2	7tmA_AT1R	29..313	CDD:320320	73/358 (20%)
		TM helix 1	30..56	CDD:320320	8/25 (32%)
		TM helix 2	63..88	CDD:320320	10/25 (40%)
		TM helix 3	101..131	CDD:320320	6/29 (21%)
		TM helix 4	144..165	CDD:320320	6/20 (30%)
		TM helix 5	192..221	CDD:320320	7/35 (20%)
		TM helix 6	233..263	CDD:320320	10/91 (11%)
		TM helix 7	281..306	CDD:320320	5/24 (21%)