Protein Alignment moody and GPR75

DIOPT Version :9

• Sequence 1: NP_001188534.1
• Gene: moody / 31168
• FlyBaseID: FBgn0025631
• Length: 670
• Species: Drosophila melanogaster
• Sequence 2: NP_006785.1
• Gene: GPR75 / 10936
• HGNCID: 4526
• Length: 540
• Species: Homo sapiens
• Alignment Length: 633
• Identity: 125/633 - (19%)
• Similarity: 209/633 - (33%)
• Gaps: 184/633 - (29%)

  Fly     8 SLEDGYPPLEALTTMVPPADATGFSQSLLTFAAVMTFLIMIV---GICGNLLTVVALLKCPKVRN 69
            ||::|...|....|:|                 ..|||:.::   |..||.:..::... |..|.
Human    28 SLQEGLQDLIHTATLV-----------------TCTFLLAVIFCLGSYGNFIVFLSFFD-PAFRK 74

  Fly    70 VAAAF---IISLCIADLLFCALVLP-FQGLRFVQGTWRHGQVLCRLIPFIQYGNIGVSLLCIAMI 130
            ....|   |::|...||..|.:..| |..:.|...........|........|.|.:||..:|:|
Human    75 FRTNFDFMILNLSFCDLFICGVTAPMFTFVLFFSSASSIPDAFCFTFHLTSSGFIIMSLKTVAVI 139

  Fly   131 TINRYVMITHHGLYA-RIYKRHWIAVMIAACWLFSYGM-QLPTLLGEWGRFGYDSRLQTCSIMTD 193
            .::|..|:.  |... |........::....|..|:.: .|.||        ..|:...|..|:.
Human   140 ALHRLRMVL--GKQPNRTASFPCTVLLTLLLWATSFTLATLATL--------KTSKSHLCLPMSS 194

  Fly   194 DHGHSSKT--TLFITAFVIPCLVIIACYAKIFWVVHKSEQ--RLKRHATKQNSIPNNLRPLASTG 254
            ......|.  :|::..|.....|:...|..|...:.|:.|  :.....|...|.|.....:...|
Human   195 LIAGKGKAILSLYVVDFTFCVAVVSVSYIMIAQTLRKNAQVRKCPPVITVDASRPQPFMGVPVQG 259

  Fly   255 SG-----ALPSGAECQPSNRVSSDSSSSFSIDVPETAPSGKQQP-------------TRVKDQRE 301
            .|     |:|:....|..|::....:..::     .:|:....|             :..||.:.
Human   260 GGDPIQCAMPALYRNQNYNKLQHVQTRGYT-----KSPNQLVTPAASRLQLVSAINLSTAKDSKA 319

  Fly   302 VRAKRNEWRITKMVLAIFLSFVVCYLP--ITIVKV---ADKNVEHPSLHICSYILLYLSACINPI 361
            |        :|.::  |.||.:||.||  |::|:|   ::.:.......:..:.|::..:.:||.
Human   320 V--------VTCVI--IVLSVLVCCLPLGISLVQVVLSSNGSFILYQFELFGFTLIFFKSGLNPF 374

  Fly   362 IYVIMNKQYRK------AYKTVVF--CQPARLLLPFGKTNGASSAAEKWKDTGLSNNHSRTIVSQ 418
            ||...:...|:      .|..:.|  |:....|...||.|             |..|.:::...:
Human   375 IYSRNSAGLRRKVLWCLQYIGLGFFCCKQKTRLRAMGKGN-------------LEVNRNKSSHHE 426

  Fly   419 MSGGTGAASGAGTATGTAAVAVMQTP-PE---VQQAQALEMVSRGPDLISKSNLPQPNVTPPPPS 479
            .:.                 |.|.:| |:   |.||       .||. .||.::..|.::
Human   427 TNS-----------------AYMLSPKPQKKFVDQA-------CGPS-HSKESMVSPKIS----- 461

  Fly   480 VLTATPNGSNSNSLTLRLPLKKNNHCYTNSGFNSSTP--------------SPSSGLGIGISSSS 530
                                ..:.||    |.:||||              |||..     .||.
Human   462 --------------------AGHQHC----GQSSSTPINTRIEPYYSIYNSSPSQE-----ESSP 497

  Fly   531 IYRPGVGSLGSGSASIRRITMVGDDIILEEEELPPTPPATSAPTTPAP 578
            .....|.|.|..::.|.......:|::.|.:       :|||...|.|
Human   498 CNLQPVNSFGFANSYIAMHYHTTNDLVQEYD-------STSAKQIPVP 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
moody	NP_001188534.1	7tm_4	44..>167	CDD:304433	29/130 (22%)
		7tm_1	53..363	CDD:278431	68/342 (20%)
		7tm_4	<310..380	CDD:304433	19/82 (23%)
GPR75	NP_006785.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..27
		7tm_1	59..>237	CDD:278431	40/188 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24228
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.100