DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4325 and RNF150

DIOPT Version :9

Sequence 1:	NP_001259169.1	Gene:	CG4325 / 31167	FlyBaseID:	FBgn0026878	Length:	158	Species:	Drosophila melanogaster
Sequence 2:	XP_005263207.1	Gene:	RNF150 / 57484	HGNCID:	23138	Length:	460	Species:	Homo sapiens

Alignment Length:	174	Identity:	37/174 - (21%)
Similarity:	69/174 - (39%)	Gaps:	40/174 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 CTICSERFRTSDNIQAGSCGHAFHEDCLDHWRKQSRTCPICRSQDAAYF----------QLYLDF 62
            |.:|.|.::.:|.::...|.|.||:.|:|.|....||||:|:.......          .|..||
Human   300 CAVCIEGYKPNDVVRILPCRHLFHKSCVDPWLLDHRTCPMCKMNILKALGIPPNADCMDDLPTDF 364

  Fly    63 EEFPESASAQGGSWGGHNRSQGHSSSSSSCSSNNNNSNDNSSSDD----YIGIMREYE------- 116
            |          ||.||...:|...:|.::.       |::|.:.|    .:|.::..:
Human   365 E----------GSLGGPPTNQITGASDTTV-------NESSVTLDPAVRTVGALQVVQDTDPIPQ 412

  Fly   117 --NLLYETGVYREEIEYLNQRIGALTVLNAELSKLHECSDSDVD 158
              ::::.|...:|.....:..|..:..:...||.:...:|.|.:
Human   413 EGDVIFTTNSEQEPAVSSDSDISLIMAMEVGLSDVELSTDQDCE 456

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4325	NP_001259169.1	zf-RING_2	8..49	CDD:290367	15/40 (38%)
CG4325	NP_001259169.1	Prefoldin	112..>151	CDD:298833	5/47 (11%)
RNF150	XP_005263207.1	PA_GRAIL_like	45..215	CDD:239037
		UPF0233	<229..>254	CDD:299753
		zf-RING_2	298..341	CDD:290367	15/40 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910