Protein Alignment Actn and micall2

DIOPT Version :10

• Sequence 1: NP_477485.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001072513.1
• Gene: micall2 / 779968
• XenbaseID: XB-GENE-979747
• Length: 1023
• Species: Xenopus tropicalis
• Alignment Length: 286
• Identity: 83/286 - (29%)
• Similarity: 132/286 - (46%)
• Gaps: 54/286 - (18%)

  Fly   147 MTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTA 211
            |.|.:.|..||:::...|::|::.|...||:|||||||::|:||||||::..|||:|..:|.:.|
 Frog     1 MAAIKALQQWCKQQCDGYRDVSITNMTTSFRDGLAFCAILHKHRPDLINFDLLSKENVYDNNHMA 65

  Fly   212 FDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYVPN 276
            |.|||:.|.||.:||.:|::....||..:|:||||.||:.|.|...:|.:..|..|       |.
 Frog    66 FSVAEEKLGIPALLDAEDMVKLRVPDRLSILTYVSQYYNYFHGRSPIGGLAGVKRP-------PP 123

  Fly   277 NYNAETAANRICK-VLKVNQENERLMEEYERLASDLLEW--------IRRTMPWLNSRQADNS-- 330
            :...|.|..::.. ||...|...|..:...|....:|:.        :|..:..::|..:.:|
 Frog   124 DTVEEPAGKKVTNDVLPTPQATSRAPQPVPRTNVPVLKSNTVIENPPVRAGIREIDSNSSVSSNC 188

  Fly   331 -LAG-----VQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQT----------KLRLSNRPAYL 379
             :.|     ||:.:.:.:.|.|        ...|.:....|||.          ....:|....:
 Frog   189 MICGKHVHLVQRHMADGKLYHR--------NCFKCKQCSRTLQPGQYKAGDGLGSFICTNHHIAV 245

  Fly   380 PT------------EGKTVSDISNSW 393
            ||            .|.||.:..:||
 Frog   246 PTSPVTRTIMPAAPHGATVDEKKSSW 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_477485.1	CH_ACTN_rpt1	31..135	CDD:409063
		CH_ACTN_rpt2	139..252	CDD:409065	49/104 (47%)
		SPEC	302..525	CDD:238103	22/130 (17%)
		SPEC	420..647	CDD:238103
		SPEC	538..760	CDD:238103
		EFh	775..842	CDD:238008
		EFhand_Ca_insen	847..913	CDD:430177
micall2	NP_001072513.1	CH_MICALL2	2..107	CDD:409102	48/104 (46%)
		LIM_Mical_like_1	188..242	CDD:188828	10/61 (16%)
		Herpes_BLLF1	<396..785	CDD:282904
		bMERB_dom	853..980	CDD:463467