Protein Alignment Actn and LOC558044

DIOPT Version :9

• Sequence 1: NP_001259165.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001093459.1
• Gene: LOC558044 / 558044
• -ID: -
• Length: 2391
• Species: Danio rerio
• Alignment Length: 1010
• Identity: 317/1010 - (31%)
• Similarity: 466/1010 - (46%)
• Gaps: 254/1010 - (25%)

  Fly    13 DGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISG 77
            :|..:|.:: |||.:        ||||||.|.||||.:....|.::..|.|:|..|:.||||:||
Zfish    81 EGRFKQLQD-EREAV--------QKKTFTKWVNSHLGRVTCRIGDLYTDLRDGRMLIRLLEVLSG 136

  Fly    78 ETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDI 142
            |.||||.:|:||.|.:.||:|||.|:..:.|||.::|:.:|||||.::|||:||||||||.||||
Zfish   137 EQLPKPTKGRMRIHCLENVDKALQFLKEQKVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDI 201

  Fly   143 SV------EEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSK 201
            ||      |:.:||:.||||||.|||.|.||||.||..|::|||||.|::|:||.||||:..|.:
Zfish   202 SVETEDNKEKKSAKDALLLWCQMKTAGYPNVNVHNFTTSWRDGLAFNAIVHKHRSDLIDFDNLKR 266

  Fly   202 DNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPE 266
            .|...||..||:||||.|.:.::|||:| :|..:|||::|:|||:.|||.|...:.:.
Zfish   267 SNAHYNLQNAFNVAEKELGLTKLLDPED-VNVDQPDEKSIITYVATYYHYFSKMKALA------- 323

  Fly   267 PTRQYTYVPNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSL 331
                           ....||.|||....|.::|:|:||.|||:||:||.:|:..||.||..|||
Zfish   324 ---------------VEGKRIGKVLDYAIEADQLIEKYETLASELLQWIEQTIVTLNDRQLANSL 373

  Fly   332 AGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGL 396
            :.||.:|:.:.|||...|||:..:|..||....|:|:|:|.:|:..|:|.|||.:|||:.:|:.|
Zfish   374 SAVQNQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERL 438

  Fly   397 ELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKK 461
            |.||...|..|..|.:|.|:||.||.:|..||...|.|. .:.:.|.|||....:|..::|..:|
Zfish   439 EKAEHERELALRNELIRQEKLEMLAARFDRKAAMRETWL-SENQRLVSQDNFGVELGAVEAATRK 502

  Fly   462 HEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTAL---- 522
            |||.|:|:.|:.:||..:.|:|:||....||:...|.||...:...|:.|..|...||..|
Zfish   503 HEAIETDIQAYGERVAAVEAVARELEAEGYHEVRRVLARRDNVLRLWEYLKELLAARRERLMAHR 567

  Fly   523 --------------------------------------------------DEAERIL-------- 529
                                                              .:|||:.
Zfish   568 DLQRLLQELSYIMEWMEDMKSRLQSQDSGKHLHDVEDLLQKHTLVEADISAQAERVKAVQATAKR 632

  Fly   530 -----------------EKIDIL---HLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEE------ 568
                             ||:|:|   :.|..:.||.....||.:|.  :..|:....||
Zfish   633 FASNEQSYKPCDPALVEEKVDLLGRAYGELGQLAADRRVRLDDSRR--LWQFLWELGEEAAWIRE 695

  Fly   569 ----IQG------------LIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPY 617
                |.|            |:..|:.|:   .|....:..:.|.:...|::||:    |.:..|.
Zfish   696 QEQIISGGDYGKDLSSALHLLSKHEAFR---DEMAARYGPLGNSIAGGEALVKE----GHVGAPE 753

  Fly   618 TTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLR-RQFAEKANIVGPWIERQMDAVTAI 681
            .|....|:..:||.:.:         |::||:|..||.:. .||...||.:..||...:..|::.
Zfish   754 VTERIKDVRAQWSHLEE---------ASQLREQSLNESVAFHQFQTDANDMEAWILETLRQVSSQ 809

  Fly   682 GMG-------------------LQG--SLEDQLHRLKEYEQAVYAYKPNI-----------EELE 714
            .:|                   :|.  ||.|.||.........||:.|.:           ||||
Zfish   810 EVGHDEFSTQTLARKQREVEEEIQSHRSLIDSLHEQGSLLPEAYAHSPQVEGRLPAIEQRYEELE 874

  Fly   715 KI----HQAVQESMIFENRYTNYTMETLRVG----W----------------------------- 742
            .:    .||:..::.....::..:...|.||    |
Zfish   875 GLSSSWRQALDGALALYRMFSEASACQLWVGEKEQWLHNMEIPTKLEDLEVIQQRFDTLEPEMNT 939

  Fly   743 ------------EQLLTSINRN---INEVENQILTR--DSKGISQEQLNEFRSSFN----HFDKN 786
                        :|||.|.|||   |::.:||:..|  |.:.::.::.....|:.|    |.:.|
Zfish   940 LGGRISDVNQVAQQLLGSDNRNKDQIDQTQNQLNNRWSDFQSLANQRKQALESALNIQNYHLECN 1004

  Fly   787 RTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRIL 821
            .......|:.|  ::....|:|.|..|.:..||.|
Zfish  1005 EIKSWMKEKTK--VIESTQSLGNDLAGVMALQRKL 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_001259165.1	CH_ACTN_rpt1	31..135	CDD:409063	53/103 (51%)
		CH_ACTN_rpt2	139..252	CDD:409065	65/118 (55%)
		SPEC	302..525	CDD:238103	92/276 (33%)
		SPEC	420..647	CDD:238103	70/330 (21%)
		SPEC	538..760	CDD:238103	67/328 (20%)
		EFh	775..842	CDD:238008	13/51 (25%)
		EFhand_Ca_insen	847..913	CDD:400872
LOC558044	NP_001093459.1	CH	94..197	CDD:237981	56/110 (51%)
		CH	213..316	CDD:237981	58/103 (56%)
		Spectrin	341..451	CDD:278843	51/109 (47%)
		SPEC	465..563	CDD:197544	34/98 (35%)
		SPEC	568..782	CDD:238103	37/231 (16%)
		SPEC	681..888	CDD:238103	48/222 (22%)
		SPEC	785..994	CDD:238103	40/208 (19%)
		SPEC	997..1201	CDD:238103	11/43 (26%)
		SPEC	1209..1419	CDD:238103
		SPEC	1420..1635	CDD:238103
		SPEC	1636..1848	CDD:238103
		SPEC	1849..2058	CDD:238103
		SPEC	2065..>2123	CDD:197544
		PH_beta_spectrin	2230..2333	CDD:269975
		PH	2230..2333	CDD:278594

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D543832at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920