Protein Alignment Actn and actn4

DIOPT Version :9

• Sequence 1: NP_001259165.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: XP_017951705.1
• Gene: actn4 / 448522
• XenbaseID: XB-GENE-494339
• Length: 926
• Species: Xenopus tropicalis
• Alignment Length: 925
• Identity: 619/925 - (66%)
• Similarity: 740/925 - (80%)
• Gaps: 44/925 - (4%)

  Fly    15 YMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEEDFRNGLKLMLLLEVISGET 79
            ||||||:|:|:.||||||||||:||||||||||||||||.|:||:||||:||||||||||||||.
 Frog    24 YMEQEEDWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGER 88

  Fly    80 LPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISV 144
            ||||:|||||.|||.||||||||||||||.|||||||||||||.|||||||||||||||||||||
 Frog    89 LPKPERGKMRVHKINNVNKALDFIASKGVKLVSIGAEEIVDGNTKMTLGMIWTIILRFAIQDISV 153

  Fly   145 EEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLN 209
            ||.:|||||||||||||||||||||||||:|:||||||.||||||||:||:|.||.||:|:.|||
 Frog   154 EETSAKEGLLLWCQRKTAPYKNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLN 218

  Fly   210 TAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYV 274
            .||:|||:|||||:|||.:|::||.:|||:|||||||.:||||.|||:
 Frog   219 NAFEVAERYLDIPKMLDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQK----------------- 266

  Fly   275 PNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLE 339
                 ||||||||||||.||||||.|||:||:||||||||||||:|||.:|..:.::..:|:|||
 Frog   267 -----AETAANRICKVLAVNQENEHLMEDYEKLASDLLEWIRRTIPWLENRVPEKTMHDMQQKLE 326

  Fly   340 EYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFE 404
            ::|.|||.||||:|::|.:||.||||||||||||||||::|:|||.||||:|.|:.||.|||.||
 Frog   327 DFRDYRRVHKPPKVQEKCQLEINFNTLQTKLRLSNRPAFMPSEGKMVSDINNGWQHLEQAEKGFE 391

  Fly   405 EWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDL 469
            ||||....|||||:|||:||:.||..||.||.|||.||:.:|:....|.::|||.:|||||||||
 Frog   392 EWLLNAIRRLERLDHLAEKFRQKALIHEAWTEGKEAMLKQKDYESATLADIKALIRKHEAFESDL 456

  Fly   470 AAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDI 534
            ||||||||||||||||||.|:|:|..|||||||:||||||.||:||..||.||:..|:.||.||.
 Frog   457 AAHQDRVEQIAAIAQELNELDYYDSPSVNARCQKICDQWDLLGSLTHTRREALEVTEKQLEAIDQ 521

  Fly   535 LHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVRE 599
            |:||:||||||||||::|..|||.|||||||:|||:|||.||:|||:||.:||:|...|:.:..|
 Frog   522 LYLEYAKRAAPFNNWMEGAMEDLQDMFIVHTIEEIEGLIAAHEQFKSTLPDADREREAILGIQNE 586

  Fly   600 VESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKA 664
            .:.|.....|.....|||||:|...:..||..|:||||:||..|..|..|||:||.||.|||..|
 Frog   587 AQKIADYSHIKLASGNPYTTVTPQIINSKWEKVQQLVPKRDGALKGEHDKQQSNEHLRLQFASLA 651

  Fly   665 NIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIEELEKIHQAVQESMIFENR 729
            |:|||||:.:|:.:..|.:.|.|:||||:..||:|||:|..|||||::||:.||.:||::||:|:
 Frog   652 NVVGPWIQAKMEEIGRIAIELHGTLEDQMTHLKQYEQSVINYKPNIDKLEQQHQLIQEALIFDNK 716

  Fly   730 YTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPE 794
            :||||||.:|||||.|||:|.|..|||||||||||:|||||||::|:|:||||||::.||.|.||
 Frog   717 HTNYTMEHIRVGWEHLLTTIARTSNEVENQILTRDAKGISQEQMHEYRASFNHFDRDHTGALGPE 781

  Fly   795 EFKSCLVSLGYSIGKDRQ----------------------GDLDFQRILAVVDPNNTGYVHFDAF 837
            |||:||:||||.:..|||                      ||.:|.||:|:|||||||.|.|.||
 Frog   782 EFKACLISLGYDVENDRQKRIGALDADDFRALLISTGYSLGDAEFNRIMAIVDPNNTGMVTFQAF 846

  Fly   838 LDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGAL 902
            :|||:||:||||||:|||.||::||.||.||...|||||||||||||||.||.||:||:.|||||
 Frog   847 IDFMSRETTDTDTADQVIASFKVLAGDKNYITAAELRRELPPDQAEYCIARMAPYQGPDAVPGAL 911

  Fly   903 DYMSFSTALYGETDL 917
            ||||||||||||:||
 Frog   912 DYMSFSTALYGESDL 926

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_001259165.1	CH_ACTN_rpt1	31..135	CDD:409063	92/103 (89%)
		CH_ACTN_rpt2	139..252	CDD:409065	87/112 (78%)
		SPEC	302..525	CDD:238103	149/222 (67%)
		SPEC	420..647	CDD:238103	136/226 (60%)
		SPEC	538..760	CDD:238103	125/221 (57%)
		EFh	775..842	CDD:238008	44/88 (50%)
		EFhand_Ca_insen	847..913	CDD:400872	51/65 (78%)
actn4	XP_017951705.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	169	1.000	Domainoid score	I3754
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	1299	1.000	Inparanoid score	I158
OMA	1	1.010	-	-		QHG54323
OrthoDB	1	1.010	-	-		D543832at2759
OrthoFinder	1	1.000	-	-		FOG0000815
OrthoInspector	1	1.000	-	-		otm49049
Panther	1	1.100	-	-	O	PTHR11915
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X512
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	10.080