Protein Alignment Actn and Smtnl2

DIOPT Version :10

• Sequence 1: NP_477485.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_808444.1
• Gene: Smtnl2 / 276829
• MGIID: 2442764
• Length: 456
• Species: Mus musculus
• Alignment Length: 184
• Identity: 57/184 - (30%)
• Similarity: 86/184 - (46%)
• Gaps: 34/184 - (18%)

  Fly    73 EVISGETLPKPDRGKMRFHKIANVNKAL-----DFIASKGVHLVSIGAEEIVDGNLKMTLGMIWT 132
            |::..:|||:....:.|        |||     ...||||            .|..:..|....:
Mouse   295 ELVRSQTLPRTSGAQAR--------KALFEKWEQDTASKG------------KGETRAKLKRSQS 339

  Fly   133 IILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYA 197
                |.:...|    :.|:.||.||:.||..|::|::|||..|:.||:|||||:|...||..||.
Mouse   340 ----FGVASAS----SIKQILLEWCRSKTVGYQHVDLQNFSSSWSDGMAFCALVHSFFPDAFDYN 396

  Fly   198 KLSKDNPLENLNTAFDVAEKYLDIPRMLDPDD-LINTPKPDERAIMTYVSCYYH 250
            .||.....:|...||.:||...:..|:::.:| ::...|||...:.|||...|:
Mouse   397 ALSPTQRQKNFELAFTMAENLANCERLIEVEDMMVMGRKPDPMCVFTYVQSLYN 450

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_477485.1	CH_ACTN_rpt1	31..135	CDD:409063	14/66 (21%)
		CH_ACTN_rpt2	139..252	CDD:409065	42/113 (37%)
		SPEC	302..525	CDD:238103
		SPEC	420..647	CDD:238103
		SPEC	538..760	CDD:238103
		EFh	775..842	CDD:238008
		EFhand_Ca_insen	847..913	CDD:430177
Smtnl2	NP_808444.1	PRK09039	<8..>84	CDD:181619
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..140
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	154..190
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	220..310		4/14 (29%)
		CH_SMTNL2	347..453	CDD:409110	41/104 (39%)