Protein Alignment Actn and ain1

DIOPT Version :9

• Sequence 1: NP_001259165.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_594295.1
• Gene: ain1 / 2542805
• PomBaseID: SPAC15A10.08
• Length: 621
• Species: Schizosaccharomyces pombe
• Alignment Length: 889
• Identity: 233/889 - (26%)
• Similarity: 362/889 - (40%)
• Gaps: 284/889 - (31%)

  Fly    32 WEKQQKKTFTAWCNSHLRKAG-TAIDNIEEDFRNGLKLMLLLEVISGETLPKPDRG-KMRFHKIA 94
            |:..|.:|||.|.|:.|.... .::.::.:|..:|:.|:.|||:|..|.|.:.:|. :||.|::.
pombe     6 WQSVQNRTFTKWFNTKLSSRDLPSVFDLRKDLSDGILLIQLLEIIGDENLGRYNRNPRMRVHRLE 70

  Fly    95 NVNKALDFIASKGVHLVSIGAEEIVDGNLKMTLGMIWTIILRFAIQDISVEEMTAKEGLLLWCQR 159
            ||||||::|.|||:.|.:||..:|||||||:.||:|||:||||.|.||:.|.:||||||||||||
pombe    71 NVNKALEYIKSKGMPLTNIGPADIVDGNLKLILGLIWTLILRFTIADINEEGLTAKEGLLLWCQR 135

  Fly   160 KTAPY-KNVNVQNFHLSFKDGLAFCALIHRHRPDLIDYAKLSKDNPLENLNTAFDVAEKYLDIPR 223
            |||.| ..|:||:|..|:.:|||||||||:|||||:||.||.|.|...|:..|||:|:|.:.|||
pombe   136 KTANYHPEVDVQDFTRSWTNGLAFCALIHQHRPDLLDYNKLDKKNHRANMQLAFDIAQKSIGIPR 200

  Fly   224 MLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQQVGNVTHVPEPTRQYTYVPNNYNAETAANRIC 288
            :::.:|:.:..:||||:|||||:.|:|||....:|                      ||||.|:.
pombe   201 LIEVEDVCDVDRPDERSIMTYVAEYFHAFSTLDKV----------------------ETAARRVE 243

  Fly   289 KVLKVNQENERLMEEYERLASDLLEWIRRTMPWLNSRQADNSLAGVQKKLEEYRTYRRKHKPPRV 353
            :..:|......:..:||.....||..|.|...:.::.|.:|:...|:.....:..::...|...|
pombe   244 RFTEVLMSTHDMKIDYESRMKRLLGSIARMQEYWHTVQFENNYTDVKSHSNNFAKFKATEKREWV 308

  Fly   354 EQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTVSDISNSWKGLELAEKAFEEWLLAETMRLERLE 418
            ::|..||:...|:||.|:......|.|..|..:.|:...||.. |:|:|.:..|:...||
pombe   309 KEKIDLESLLGTIQTNLKTYQLRKYEPPAGLKIVDLERQWKDF-LSEEANQSKLINTHMR----- 367

  Fly   419 HLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCKLNELKALKKKHEAFESDLAAHQDRVEQIAAIA 483
                                               |:|
pombe   368 -----------------------------------EIK--------------------------- 370

  Fly   484 QELNTLEYHDCVSVNARCQRICDQWDRLGALTQRRRTALDEAERILEKIDILHLEFAKRAAPFNN 548
                                                             :.:.:.||.||..|:.
pombe   371 -------------------------------------------------ESMRIAFADRANSFSK 386

  Fly   549 WLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKATLGEADKEFNLIVNLVREVESIVKQHQIPGGL 613
            .|
pombe   387 ML--------------------------------------------------------------- 388

  Fly   614 ENPYTTLTANDMTRKWSDVRQLVPQRDQTLANELRKQQNNEMLRRQFAEKANIVGPWIERQMDAV 678
                                       .|::||:                .|:.|.|.: |:|.|
pombe   389 ---------------------------STISNEI----------------TNLQGDWRD-QLDHV 409

  Fly   679 TAIGMGLQGSLEDQLHRLKEYEQAVY--AYKPNIEELEKIHQAVQESMIFENRYTNYTMETLRVG 741
            ..:...| |.||.:|..:|    .:|  .::..||               ||.||.::.|.|...
pombe   410 EFLQEHL-GPLEVELASVK----VLYDNCFQAGIE---------------ENDYTMFSYEDLEHE 454

  Fly   742 WEQLLTSINRNINEVENQILTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYS 806
            :......|...|..:||::|.|:.:.:|:::|:.....|.||:|.::..|:..||.:.|.|||.
pombe   455 FGITANIIANKIKYLENELLEREKRTLSKQELDGITKVFRHFEKKKSNMLNEVEFYAALASLGL- 518

  Fly   807 IGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPD 871
            :....:|...|.|.     .|:...|.::.|.:.:..|..|.|:|.||:.:|..:|..|.|:..|
pombe   519 VYDTEEGTALFHRA-----ANSEEGVTYERFTEIVMEELEDRDSARQVLYAFCDVADGKSYVTSD 578

  Fly   872 E-LRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMSFSTALYGE 914
            : ||.::.|:..::....|      |.....|||:::...|..|
pombe   579 DLLRSQVRPNIVKFLECNM------NKHSEGLDYLTWIKQLLAE 616

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_001259165.1	CH_ACTN_rpt1	31..135	CDD:409063	46/104 (44%)
		CH_ACTN_rpt2	139..252	CDD:409065	66/113 (58%)
		SPEC	302..525	CDD:238103	32/222 (14%)
		SPEC	420..647	CDD:238103	10/226 (4%)
		SPEC	538..760	CDD:238103	34/223 (15%)
		EFh	775..842	CDD:238008	17/66 (26%)
		EFhand_Ca_insen	847..913	CDD:400872	19/66 (29%)
ain1	NP_594295.1	SAC6	1..616	CDD:227401	232/887 (26%)
		CH	9..113	CDD:237981	47/103 (46%)
		CH	125..229	CDD:237981	61/103 (59%)
		EFhand_Ca_insen	554..615	CDD:285885	19/66 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	134	1.000	Domainoid score	I1282
eggNOG	1	0.900	-	-		E2759_KOG0035
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54323
OrthoFinder	1	1.000	-	-		FOG0000815
OrthoInspector	1	1.000	-	-		otm47215
orthoMCL	1	0.900	-	-		OOG6_101135
Panther	1	1.100	-	-	O	PTHR11915
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R34
SonicParanoid	1	1.000	-	-		X512
TreeFam	1	0.960	-	-
	11	10.810