DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Actn and actn2a

DIOPT Version :9

Sequence 1:	NP_001259165.1	Gene:	Actn / 31166	FlyBaseID:	FBgn0000667	Length:	917	Species:	Drosophila melanogaster
Sequence 2:	XP_009298993.1	Gene:	actn2a / 100538165	ZFINID:	ZDB-GENE-141114-2	Length:	152	Species:	Danio rerio

Alignment Length:	157	Identity:	104/157 - (66%)
Similarity:	133/157 - (84%)	Gaps:	5/157 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   761 LTRDSKGISQEQLNEFRSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVD 825
            :|||:|||||:|||:|||||.|||:.:.|.:..::|::||:|:||.:     |:.:|.||:|:||
Zfish     1 MTRDAKGISQKQLNDFRSSFTHFDRKKKGGMETDDFRACLISMGYDL-----GEAEFARIMALVD 60

  Fly   826 PNNTGYVHFDAFLDFMTRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMP 890
            ||.:|.|.|.||:||||||:.::||:|||:.|||||||||||||.|||||||||:||||||.|||
Zfish    61 PNGSGVVTFQAFVDFMTRETGESDTSEQVVASFRILAADKPYILLDELRRELPPEQAEYCISRMP 125

  Fly   891 PYKGPNGVPGALDYMSFSTALYGETDL 917
            |||||:.|||||||.:||||||||:||
Zfish   126 PYKGPDAVPGALDYAAFSTALYGESDL 152

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_001259165.1	CH_ACTN_rpt1	31..135	CDD:409063
		CH_ACTN_rpt2	139..252	CDD:409065
		SPEC	302..525	CDD:238103
		SPEC	420..647	CDD:238103
		SPEC	538..760	CDD:238103
		EFh	775..842	CDD:238008	31/66 (47%)
		EFhand_Ca_insen	847..913	CDD:400872	53/65 (82%)
actn2a	XP_009298993.1	EFh	15..77	CDD:238008	31/66 (47%)
		EF-hand_7	17..76	CDD:290234	29/63 (46%)
		EFhand_Ca_insen	82..148	CDD:285885	53/65 (82%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D543832at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.010