Protein Alignment Actn and zgc:165653

DIOPT Version :10

• Sequence 1: NP_477485.1
• Gene: Actn / 31166
• FlyBaseID: FBgn0000667
• Length: 917
• Species: Drosophila melanogaster
• Sequence 2: NP_001429602.1
• Gene: zgc:165653 / 100006671
• ZFINID: ZDB-GENE-070620-24
• Length: 896
• Species: Danio rerio
• Alignment Length: 921
• Identity: 607/921 - (65%)
• Similarity: 748/921 - (81%)
• Gaps: 31/921 - (3%)

  Fly     1 MMME---NGLSMEYG-DGYMEQEEEWEREGLLDPAWEKQQKKTFTAWCNSHLRKAGTAIDNIEED 61
            ||||   |..:..|| :.||.||:||:|:.||||||||||:||||||||||||||||.|:|||||
Zfish     3 MMMEMQYNNNNNGYGVEEYMIQEDEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEED 67

  Fly    62 FRNGLKLMLLLEVISGETLPKPDRGKMRFHKIANVNKALDFIASKGVHLVSIGAEEIVDGNLKMT 126
            ||||||||||||:||||.|.||||||||||||||||||||:|.||||.|||||||||||||:|||
Zfish    68 FRNGLKLMLLLELISGERLAKPDRGKMRFHKIANVNKALDYITSKGVKLVSIGAEEIVDGNVKMT 132

  Fly   127 LGMIWTIILRFAIQDISVEEMTAKEGLLLWCQRKTAPYKNVNVQNFHLSFKDGLAFCALIHRHRP 191
            ||||||||||||||||||||.:||||||||||||||||:||||||||.|:|||||||||||||||
Zfish   133 LGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPYRNVNVQNFHCSWKDGLAFCALIHRHRP 197

  Fly   192 DLIDYAKLSKDNPLENLNTAFDVAEKYLDIPRMLDPDDLINTPKPDERAIMTYVSCYYHAFQGAQ 256
            ||||::||:|::||.|||.|.::|||:||||:||||:|:|||||||||||||||||:||||.||:
Zfish   198 DLIDFSKLNKEDPLGNLNLALEIAEKHLDIPKMLDPEDIINTPKPDERAIMTYVSCFYHAFAGAE 262

  Fly   257 QVGNVTHVPEPTRQYTYVPNNYNAETAANRICKVLKVNQENERLMEEYERLASDLLEWIRRTMPW 321
            |                      ||||||||||||.||||||:||||||||||:||||||||.||
Zfish   263 Q----------------------AETAANRICKVLGVNQENEKLMEEYERLASELLEWIRRTTPW 305

  Fly   322 LNSRQADNSLAGVQKKLEEYRTYRRKHKPPRVEQKAKLETNFNTLQTKLRLSNRPAYLPTEGKTV 386
            |..|.|:|::|..::|||:||.|||.||||:|::|.:||.:|||||||||:|||||::|:|||.|
Zfish   306 LEKRAAENTMASTRRKLEDYRDYRRVHKPPKVQEKCQLEISFNTLQTKLRISNRPAFMPSEGKMV 370

  Fly   387 SDISNSWKGLELAEKAFEEWLLAETMRLERLEHLAQKFKHKADAHEDWTRGKEEMLQSQDFRQCK 451
            |||:.:|:|||.|||.:|||||:|..||||:||||:||:.|...||.|.:||:::|..:|:....
Zfish   371 SDITAAWQGLEQAEKGYEEWLLSEIRRLERVEHLAEKFQQKVSTHESWAQGKDQLLTLKDYESGS 435

  Fly   452 LNELKALKKKHEAFESDLAAHQDRVEQIAAIAQELNTLEYHDCVSVNARCQRICDQWDRLGALTQ 516
            |.:::||.:|||||||||||||||||||||||||||.|:||....:|.|||.||||||:||.|||
Zfish   436 LTDVRALLRKHEAFESDLAAHQDRVEQIAAIAQELNELDYHAAAVINERCQSICDQWDQLGTLTQ 500

  Fly   517 RRRTALDEAERILEKIDILHLEFAKRAAPFNNWLDGTREDLVDMFIVHTMEEIQGLIQAHDQFKA 581
            :||.||:..|::||.||.|.||||||:||||||:||..|||.|||:||:::|:|.|:.||||||.
Zfish   501 KRREALERTEKLLETIDQLFLEFAKRSAPFNNWMDGAMEDLQDMFMVHSIDEVQNLLSAHDQFKV 565

  Fly   582 TLGEADKEFNLIVNLVREVESIVKQHQIPGGLENPYTTLTANDMTRKWSDVRQLVPQRDQTLANE 646
            ||.|||.|...|:::..||:.|.:.:.|...|.|.|.::|..|:.:||..|::||||||..|..|
Zfish   566 TLPEADSERQAIMSIYNEVQKICQSYGISSKLSNIYCSITPADLNQKWEKVKRLVPQRDSALHEE 630

  Fly   647 LRKQQNNEMLRRQFAEKANIVGPWIERQMDAVTAIGMGLQGSLEDQLHRLKEYEQAVYAYKPNIE 711
            ..:|..||.||||||.:||.:||||:.:|:.:....:.|..:||||::.||:||..:.:|||||:
Zfish   631 FSRQNVNERLRRQFAGQANAIGPWIQTRMEEIAHSTVDLGTTLEDQMNTLKQYEHDIISYKPNID 695

  Fly   712 ELEKIHQAVQESMIFENRYTNYTMETLRVGWEQLLTSINRNINEVENQILTRDSKGISQEQLNEF 776
            :||..||.:|||:||:|::||||||.:|||||.|||:|.|.|||:|.||:|||:|||||:|||:|
Zfish   696 KLEGDHQLIQESLIFDNKHTNYTMEHIRVGWESLLTTIARTINEIETQIMTRDAKGISQKQLNDF 760

  Fly   777 RSSFNHFDKNRTGRLSPEEFKSCLVSLGYSIGKDRQGDLDFQRILAVVDPNNTGYVHFDAFLDFM 841
            ||||.|||:.:.|.:..::|::||:|:||.:     |:.:|.||:|:||||.:|.|.|.||:|||
Zfish   761 RSSFTHFDRKKKGGMETDDFRACLISMGYDL-----GEAEFARIMALVDPNGSGVVTFQAFVDFM 820

  Fly   842 TRESTDTDTAEQVIDSFRILAADKPYILPDELRRELPPDQAEYCIQRMPPYKGPNGVPGALDYMS 906
            |||:.::||:|||:.|||||||||||||.|||||||||:||||||.||||||||:.|||||||.:
Zfish   821 TRETGESDTSEQVVASFRILAADKPYILVDELRRELPPEQAEYCISRMPPYKGPDAVPGALDYAA 885

  Fly   907 FSTALYGETDL 917
            ||||||||:||
Zfish   886 FSTALYGESDL 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Actn	NP_477485.1	CH_ACTN_rpt1	31..135	CDD:409063	93/103 (90%)
		CH_ACTN_rpt2	139..252	CDD:409065	92/112 (82%)
		SPEC	302..525	CDD:238103	144/222 (65%)
		SPEC	420..647	CDD:238103	127/226 (56%)
		SPEC	538..760	CDD:238103	117/221 (53%)
		EFh	775..842	CDD:238008	31/66 (47%)
		EFhand_Ca_insen	847..913	CDD:430177	53/65 (82%)
zgc:165653	NP_001429602.1	None