Protein Alignment usp and nhr-168

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001256501.1
• Gene: nhr-168 / 353455
• WormBaseID: WBGene00008221
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 465
• Identity: 105/465 - (22%)
• Similarity: 176/465 - (37%)
• Gaps: 123/465 - (26%)

  Fly    55 PGSNSASSNNNSAGD-----AQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGK 114
            ||.:..||.::...|     :.:.:.||....|.:.|.|:...|:.        |||||..|:|.
 Worm     4 PGCSKVSSVDSIDFDFPELPSIIQKEPNRTARSESPARQRHQRPSE--------CSICGKTANGY 60

  Fly   115 HYGVYSCEGCKGFFKRTVRKDLTYACRENRNCI-IDKRQ-RNRCQYCRYQKCLTCGMKREA-VQE 176
            ||.|.||.|||.||:|....:.::.|:...:|. :.||: ..:|:.|||:||::.||...| :.:
 Worm    61 HYDVPSCNGCKTFFRRLCVSEKSFICKAGGDCFNLTKRKVPLKCRACRYEKCISEGMNPNAMLLD 125

  Fly   177 ERQRGARN---AAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDF--------- 229
            |::..|.|   ...|::     .|.|......|      |..:...:.......|.
 Worm   126 EKEATAENFKKLKKRVN-----QSNPKDPDDDS------GEDIEHQIEKKQVIKDVACIENKMQK 179

  Fly   230 ---MTNSVSRDFSIERIIEAEQRAETQCGDRALTFL--------RVGP----------------- 266
               |.|.:.|..:..|:........|..|..|...|        |.||
 Worm   180 LVDMLNYLERKVTKFRMSAYNPHWSTLPGLEAFLLLENKISLADRSGPMPGWPLKTQSSPPKIPE 244

  Fly   267 ---------YSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELL 322
                     ||   ||.|      |.:: ..|...:|||:....|.|:...|:::|::...:.|:
 Worm   245 FGKKPTGPAYS---PDQK------CWIL-YDLMVSIEYAKTFMFFHQLDSRDRLVLMRYVALALM 299

  Fly   323 IANVAWCSIVSLDDGGAGGGGGGLGH-DGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIF 386
            ..::::.::....|        .:.| ||.       |.|                :|.|:  ::
 Worm   300 NLHISYFTVAKKYD--------TIIHPDGK-------LAP----------------MKKGM--VY 331

  Fly   387 DRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREK-VYA-CLDEHCRLEHP 449
            ...:..:: .:.|..:...|...||||.|.||.:..:...|:..:.||: .|| .|.:||.....
 Worm   332 AETVMSIA-PLIRCEIQETEFVLLKAICLCNPAVPDLSQHAQEILGREREQYADALFDHCLRNRK 395

  Fly   450 GDDGRFAQLL 459
            ....:||:|:
 Worm   396 DGPSQFAELI 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	31/78 (40%)
		NR_LBD_RXR_like	237..480	CDD:132741	51/260 (20%)
nhr-168	NP_001256501.1	ZnF_C4	50..120	CDD:197701	30/69 (43%)
		HOLI	264..414	CDD:214658	37/176 (21%)