Protein Alignment usp and HNF4G

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_004124.5
• Gene: HNF4G / 3174
• HGNCID: 5026
• Length: 455
• Species: Homo sapiens
• Alignment Length: 455
• Identity: 130/455 - (28%)
• Similarity: 209/455 - (45%)
• Gaps: 110/455 - (24%)

  Fly    61 SSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCK 125
            :|:::||.:..|....|                     |...||:||||||:|||||..||:|||
Human    37 NSSDSSAPETSMNTTDN---------------------GVNCLCAICGDRATGKHYGASSCDGCK 80

  Fly   126 GFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLS 190
            |||:|::||...|:||.:|.|::||.:||:|:|||.:||...|||:||||.||.|     .....
Human    81 GFFRRSIRKSHVYSCRFSRQCVVDKDKRNQCRYCRLRKCFRAGMKKEAVQNERDR-----ISTRR 140

  Fly   191 ASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCG 255
            ::..||:.|                                       ||..:.:||.|:
Human   141 STFDGSNIP---------------------------------------SINTLAQAEVRS----- 161

  Fly   256 DRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIE 320
             |.::....|..:.:......::..:|:.:.:||..:||:|:.:|.|.::||||||.||:|...|
Human   162 -RQISVSSPGSSTDINVKKIASIGDVCESMKQQLLVLVEWAKYIPAFCELPLDDQVALLRAHAGE 225

  Fly   321 LLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAI 385
            .|:......|::..|                           .|.|..::..||||. :..:|.:
Human   226 HLLLGATKRSMMYKD---------------------------ILLLGNNYVIHRNSC-EVEISRV 262

  Fly   386 FDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPG 450
            .:|:|.||....:.:.:|..|.:|||||:.::||.:|:....:|:..|.:|...|:::.......
Human   263 ANRVLDELVRPFQEIQIDDNEYACLKAIVFFDPDAKGLSDPVKIKNMRFQVQIGLEDYINDRQYD 327

  Fly   451 DDGRFAQLLLRLPALRSISLKCQDHLFLFR----ITSDRPLEELFL-------EQLEAPPPPGLA 504
            ..|||.:|||.||.|:||:.:..:.:...:    :..|..|:|:.|       ..|..|..|.|:
Human   328 SRGRFGELLLLLPTLQSITWQMIEQIQFVKLFGMVKIDNLLQEMLLGGASNDGSHLHHPMHPHLS 392

  Fly   505  504
            Human   393  392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	46/75 (61%)
		NR_LBD_RXR_like	237..480	CDD:132741	64/242 (26%)
HNF4G	NP_004124.5	NR_DBD_HNF4A	59..134	CDD:143518	46/74 (62%)
		NR_LBD_HNF4_like	150..371	CDD:132729	66/254 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165144372
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840