Protein Alignment usp and Rxrb

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001192143.1
• Gene: Rxrb / 20182
• MGIID: 98215
• Length: 524
• Species: Mus musculus
• Alignment Length: 531
• Identity: 214/531 - (40%)
• Similarity: 273/531 - (51%)
• Gaps: 138/531 - (25%)

  Fly    26 LNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAP-------------- 76
            :.||...|.||.:.||.|..|.     :.|.|........||....|...|
Mouse    70 MGDSGRDSRSPDSSSPNPLSQG-----IRPSSPPGPPLTPSAPPPPMPPPPLGSPFPVISSSMGS 129

  Fly    77 --------------------NS-----AGGS-----------AAAAVQQQYPPNHPLSGSKHLCS 105
                                ||     .|||           ....:....||..|.:| |.||:
Mouse   130 PGLPPPAPPGFSGPVSSPQINSTVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPGGPGAG-KRLCA 193

  Fly   106 ICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMK 170
            |||||:||||||||||||||||||||:||||||:||:|::|.:|||||||||||||||||..|||
Mouse   194 ICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCRYQKCLATGMK 258

  Fly   171 REAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVS 235
            ||||||||||                       |....|.|.|.|                 ...
Mouse   259 REAVQEERQR-----------------------GKDKDGDGDGAG-----------------GAP 283

  Fly   236 RDFSIERIIEAEQRAETQCGDRALTFLRVGPYST----VQPDYKGAVSALCQVVNKQLFQMVEYA 296
            .:..::||:|||...| |..|:.:.    ||.:|    ..|:  ..|:.:||..:||||.:||:|
Mouse   284 EEMPVDRILEAELAVE-QKSDQGVE----GPGATGGGGSSPN--DPVTNICQAADKQLFTLVEWA 341

  Fly   297 RMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQP 361
            :.:|||:.:|||||||||:|.|.|||||                          ||..||..::
Mouse   342 KRIPHFSSLPLDDQVILLRAGWNELLIA--------------------------SFSHRSIDVR- 379

  Fly   362 QQLFLNQSFSYHRNSAIKAGVSAIFD----RILSELSVKMKRLNLDRRELSCLKAIILYNPDIRG 422
            ..:.|......|||||..|||.||||    |:|:||..||:.:.:|:.||.||:||||:|||.:|
Mouse   380 DGILLATGLHVHRNSAHSAGVGAIFDRSLSRVLTELVSKMRDMRMDKTELGCLRAIILFNPDAKG 444

  Fly   423 IKSRAEIEMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPL 487
            :.:..|:|:.||||||.|:.:|:.::|...||||:|||||||||||.|||.:|||.|::..|.|:
Mouse   445 LSNPGEVEILREKVYASLETYCKQKYPEQQGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPI 509

  Fly   488 EELFLEQLEAP 498
            :...:|.||||
Mouse   510 DTFLMEMLEAP 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	63/75 (84%)
		NR_LBD_RXR_like	237..480	CDD:132741	109/250 (44%)
Rxrb	NP_001192143.1	Modulating. /evidence=ECO:0000250	1..191		25/126 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..167		20/101 (20%)
		Nuc_recep-AF1	<122..176	CDD:288658	5/53 (9%)
		NR_DBD_RXR	191..266	CDD:143514	63/74 (85%)
		Hinge	258..382		61/197 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	263..285		11/61 (18%)
		NR_LBD_RXR_like	285..502	CDD:132741	109/250 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	300..323		6/28 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834508
Domainoid	1	1.000	189	1.000	Domainoid score	I3286
eggNOG	1	0.900	-	-		E33208_3BA8J
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	363	1.000	Inparanoid score	I2163
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D389616at33208
OrthoFinder	1	1.000	-	-		FOG0001500
OrthoInspector	1	1.000	-	-		otm44370
orthoMCL	1	0.900	-	-		OOG6_103349
Panther	1	1.100	-	-	O	PTHR24083
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4818
SonicParanoid	1	1.000	-	-		X118
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.790