Protein Alignment usp and nhr-221

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_503987.1
• Gene: nhr-221 / 188826
• WormBaseID: WBGene00020748
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 409
• Identity: 84/409 - (20%)
• Similarity: 138/409 - (33%)
• Gaps: 132/409 - (32%)

  Fly    97 LSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRN----RCQ 157
            |..||  |.:|...|.|.|..|.:|:|||.||:|.........|..:.:| .|..:||    ||:
 Worm    29 LKPSK--CMVCVRPAHGYHCDVATCKGCKTFFRRMCLLRGEIKCSTSGDC-YDLEKRNSPLLRCR 90

  Fly   158 YCRYQKCLTCGMKREAV---------------QEERQRGARNAAGRLSASGGGSSGPGSVGGSSS 207
            .||:::||..||..:|:               .|::.:|..:....|.|.
 Worm    91 PCRFKRCLLVGMNPKALIIDGSNILGEKQVHFNEQQIQGTIDVLSHLEAK--------------- 140

  Fly   208 QGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIE-AEQRAETQCGDRALTFLRVGPYSTVQ 271
                              ::.|...:.:.|::..|:.: ....::....|:..||
 Worm   141 ------------------TEQFSKCAYNPDWTNIRLKDLILSPSKLSMSDKVGTF---------- 177

  Fly   272 PDYKGAVSALC-------QVVNK---------------QLFQMVEYARMMPHFAQVPLDDQVILL 314
            ||:     .||       |:|::               .|...|||.:....|..:...||:.||
 Worm   178 PDW-----PLCPNYEFPDQIVHRDIQSFSPHRKQWRFSNLMTAVEYTKTFSFFHDLSFQDQINLL 237

  Fly   315 KAAWIELLIANVAWCSIVS-LDDGGAGGGGGGLGHDGSFERRSPGL-QPQQLFLNQSFSYHRNSA 377
            |...|.|...|..:.::.: .||         |......:|  ||: :|........|.
 Worm   238 KHVVIGLANFNTTYYTLKNKFDD---------LRQPDGTQR--PGVNEPHYCAHTVPFG------ 285

  Fly   378 IKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAE--IEMCREKVYACL 440
                              .|||:.:...|...||.:.:.||.:..:...|:  ||..|......|
 Worm   286 ------------------PMKRIKIQFNEFLLLKILFVCNPAVPNLSKHAQFVIEKERHHYSNIL 332

  Fly   441 DEHCRLEHPGDDGRFAQLL 459
            .::|...:.....||.:|:
 Worm   333 LKYCLQNYSYGPTRFVELI 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	28/94 (30%)
		NR_LBD_RXR_like	237..480	CDD:132741	49/250 (20%)
nhr-221	NP_503987.1	ZnF_C4	33..105	CDD:197701	27/74 (36%)
		HOLI	209..360	CDD:214658	38/178 (21%)