Protein Alignment usp and nhr-189

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_504065.2
• Gene: nhr-189 / 185913
• WormBaseID: WBGene00018545
• Length: 355
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 79/388 - (20%)
• Similarity: 138/388 - (35%)
• Gaps: 126/388 - (32%)

  Fly   104 CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQR-NRCQYCRYQKCLTC 167
            |:|||..||..:|||.||..||.||:|.|.:.|||.|::...|:.:..|. .:|:.||::|||..
 Worm    22 CTICGRDASCHNYGVLSCNACKMFFRRVVIEQLTYHCKKWNMCLENSGQPILQCKACRFEKCLQL 86

  Fly   168 GM---KREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDF 229
            ||   :.|.:|
 Worm    87 GMTLGQLEKIQ------------------------------------------------------ 97

  Fly   230 MTNSVSRDFSIERIIEAEQRAETQCGDRALTFLRVGPYSTVQPDYKGAV-----SALCQVVNKQL 289
            :.:.:..||..:.:|:......:....:...|     |::..|..:..|     |.:.:...||:
 Worm    98 LPDLIHPDFKSDSLIKNVMFLNSTKRFKLCNF-----YTSEDPTLEDMVQRTKRSRMKRKTGKQV 157

  Fly   290 FQMVEYARMMPHFA-----------QVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGG 343
            ..:.|::....:.|           .:..||:::||:
 Worm   158 ISVEEWSFQAIYIAVEMFLSLDFMNSIENDDKIVLLR---------------------------- 194

  Fly   344 GGLGHDGSFERRSPGLQPQQLFLN----QSFSYHRNSAIKAGVSAIF-----DRILSELSVKMKR 399
                   :|..:|..|......||    :..:...|......:.|:|     :.|.|.|.|:::.
 Worm   195 -------NFSSKSMQLDSAMRSLNAKVDRVITPDGNEVYSDLLLAMFSIDFLNSIRSSLVVRVEE 252

  Fly   400 LNLDRRELSCLKAIILYNPDIRGIKSRA-EIEMCREKVY-ACLDEHCRLEH-PGDDGRFAQLL 459
            |.:..:|.:.|..::..||.|..:..|. .:...|:|.| :.|.::|.|.: .....|||.||
 Worm   253 LKVTEQEHALLNFLLFCNPAIHPLSERTRRLLATRQKSYSSALLQYCLLTYQQSGPSRFADLL 315

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	33/77 (43%)
		NR_LBD_RXR_like	237..480	CDD:132741	46/251 (18%)
nhr-189	NP_504065.2	ZnF_C4	21..89	CDD:197701	30/66 (45%)
		HOLI	164..324	CDD:214658	35/187 (19%)