Protein Alignment usp and nhr-185

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_504061.2
• Gene: nhr-185 / 185907
• WormBaseID: WBGene00018539
• Length: 390
• Species: Caenorhabditis elegans
• Alignment Length: 413
• Identity: 88/413 - (21%)
• Similarity: 158/413 - (38%)
• Gaps: 105/413 - (25%)

  Fly    90 QYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIID---KR 151
            |..||..:.     ||:|...|.|.:|||.||..||.||:|......:|.|..:.:|..:   ..
 Worm    22 QLVPNCSIQ-----CSVCCQLAFGLNYGVPSCNACKMFFRRMNIIKPSYTCLADGSCYTNFGFTH 81

  Fly   152 QRNRCQYCRYQKCLTCGMKREAVQEERQR---GARNAAGRLSASGGGSSGPGSVGGSSSQGGGGG 213
            .|.:|:.||::|||..|||..:.:||.:.   ..:::..:|.
 Worm    82 GRPKCRSCRFRKCLDVGMKYRSTEEEDEMMLIMLKSSTAQLQ----------------------- 123

  Fly   214 GGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQR----AETQCGDRALTF-----LRVGPYST 269
                        .|.|:|.:.....||..:.:.:.|    .||...|...|.     ..:..::|
 Worm   124 ------------PDIFVTVADELYGSINSLRQLDARRAMNLETMRSDEDPTIEDLIKKSIRGFTT 176

  Fly   270 VQ-PDYKGAVSALCQVVNKQLF----QMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAW- 328
            :| |.....|....||:::..|    ..||:...:...:.:.::|::|:||:..:...:.:.|:
 Worm   177 IQNPGSSQLVHQADQVLSQWTFFGIWTSVEFLNSLDFMSLLGIEDKLIVLKSFALSSYLLSSAFH 241

  Fly   329 -CS-----IVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFD 387
             ||     :|:.|                      |.:.....:.:...:.::.|         |
 Worm   242 SCSRCCDRLVNPD----------------------GTELYSSRIREMSEFSKDYA---------D 275

  Fly   388 RILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRA-EIEMCREKVYA-CLDEHCRL-EHP 449
            ||...|..|:..|.|...|....:.|:...|.:.|:...| ||...::|.|. .|.|:|:| .:.
 Worm   276 RIQEMLVTKICGLCLTPEEYILTQIILFCTPRLTGLSQFAQEIIGEQQKKYCNSLLEYCKLTRNT 340

  Fly   450 GDDGRFAQLLLRLPALRSISLKC 472
            ....||.:::    ::.|:..:|
 Worm   341 RGPARFQEII----SIGSVLAQC 359

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	29/78 (37%)
		NR_LBD_RXR_like	237..480	CDD:132741	51/260 (20%)
nhr-185	NP_504061.2	ZnF_C4	31..100	CDD:197701	26/68 (38%)
		HOLI	197..356	CDD:214658	37/193 (19%)