Protein Alignment usp and nhr-133

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_503602.1
• Gene: nhr-133 / 185729
• WormBaseID: WBGene00003723
• Length: 406
• Species: Caenorhabditis elegans
• Alignment Length: 433
• Identity: 97/433 - (22%)
• Similarity: 157/433 - (36%)
• Gaps: 107/433 - (24%)

  Fly    92 PPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTY---ACRENRNCIIDKRQR 153
            ||...|||.   |.||...|.|.|:||.||..|..||:|...::..|   .||:. |||  ....
 Worm     2 PPALYLSGP---CEICEQPAHGNHFGVLSCRACAAFFRRAALQNAKYQDRVCRKG-NCI--GNDL 60

  Fly   154 NRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSG 218
            .||:.||.:||...||.....|.:|.         |.:|   |..|.:...:|:         ..
 Worm    61 YRCKICRLKKCCEVGMNSSKFQNDRD---------LISS---SLRPTNYTKTSA---------PQ 104

  Fly   219 GMGSGNGSDDF-MTNSVSRDFSIERIIEAEQRAETQCGDRA-LTFLRVGPYSTVQPDYKGAVSAL 281
            .:.:..|..:| :.....:..|.:|:::.     |...|:| ..|.....||.....|..::..|
 Worm   105 SLANFLGRPEFILCCEPDKASSTKRLVDV-----TSLVDKAWAIFQEDAAYSWSPNHYPNSLEKL 164

  Fly   282 C----QVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAW-------------IELLIANVAWC 329
            .    ::..|:..:.:|.|..:.....:...:|..|..|.|             |::.|...:|.
 Worm   165 TFEMEEIKLKESSKKLEIATTIGRNEALLFLEQSFLGAAQWFARLPEFSMLDPQIKIDILKTSWM 229

  Fly   330 SIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELS 394
            ....||.         |.....|.|       |:|..|..:.:..|:.:..|...|..:..|..|
 Worm   230 IWARLDK---------LAATADFHR-------QKLLGNDVYMWTDNTCMNPGNVKIDIKWSSNYS 278

  Fly   395 VKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYA-CLDEHCRLEHPGDDGRFAQL 458
            |:.            |:..::  |||             ||.:. .|.:...|:....:..|  :
 Worm   279 VEQ------------LRGFLV--PDI-------------EKYWRHALSDLVELDPTNVELNF--M 314

  Fly   459 LLRLPALRSISLKCQDHLF-----LFRITSDRPLEELFLEQLE 496
            |::| .|.|...|.|.|:.     :.:|.||. :.|.:.::|:
 Worm   315 LIQL-CLNSAGQKYQGHVLEATEKILQIQSDN-MHEYYTKKLK 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	29/78 (37%)
		NR_LBD_RXR_like	237..480	CDD:132741	50/266 (19%)
nhr-133	NP_503602.1	NR_DBD_like	11..86	CDD:295381	29/77 (38%)
		Hormone_recep	176..383	CDD:278530	44/227 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1511
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.950