Protein Alignment usp and nhr-141

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001023845.2
• Gene: nhr-141 / 184926
• WormBaseID: WBGene00017787
• Length: 433
• Species: Caenorhabditis elegans
• Alignment Length: 488
• Identity: 100/488 - (20%)
• Similarity: 176/488 - (36%)
• Gaps: 128/488 - (26%)

  Fly    61 SSNNNSAG---DAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCE 122
            |.:|.::|   |....|..:....|..:..|:...|..        ||:||.:|:|.||.|.||.
 Worm     5 SCSNIASGESLDLNWPQRLSDCKMSKESTFQRHPRPTE--------CSVCGKKATGYHYDVPSCN 61

  Fly   123 GCKGFFKRTVRKDLTYACRENRNCI-IDKR-QRNRCQYCRYQKCLTCGMKREAVQ-EERQRGARN 184
            |||.||:|....:.|..|:...:|. :.|| ...:|:.||::||:..||...|:| :|::..|:|
 Worm    62 GCKTFFRRICISEKTMQCQGVGDCFDLTKRIAPVKCRACRFEKCVLKGMNPNAMQIDEKEESAKN 126

  Fly   185 AAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSR-DFSIERIIEAEQ 248
            .......................|                     ..||:.. :..::::::|..
 Worm   127 YKHLKKLKNQYCQKDSEHSMEKKQ---------------------TINSIDAIETKMQKLVDALS 170

  Fly   249 RAETQ-----------------CGDRALTF-----------------LRVGPYSTVQPDYKGAVS 279
            ..|.:                 |.:..|..                 |:..|.....|:::...|
 Worm   171 YLEIKLRKFRLSAYNPHWSTIPCLEEFLLLENKICLADKSGPMPGWPLKTQPAPPKIPEFRNNPS 235

  Fly   280 ALCQVVNKQ------LFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGG 338
            ......:|:      |...:|||:....|.|:...|::||::...:.|:..::::.::....|
 Worm   236 GRPYFPDKKTWLLYDLMVSIEYAKTFMFFHQLGTRDRLILMRYVSLALMNLHISYFTVAKKFD-- 298

  Fly   339 AGGGGGGLGH-DGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVKMK---R 399
                  .:.| |||....:.|:                             :.:|..:.|.   |
 Worm   299 ------TIIHPDGSLAPMNKGM-----------------------------VYAETVMSMAPLIR 328

  Fly   400 LNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREK-VYA-CLDEHCRLEHPGDDGRFAQLLLRL 462
            .|:...|...||||.|.||.:..:.:.|:..:.:|: .|| .|.:||.........:||:|:..:
 Worm   329 CNIQEIEYILLKAICLCNPAVPELSTHAQKILAKEREQYADALFDHCIRSRTNGPAQFAELISMV 393

  Fly   463 PALRSISLKCQDHLFLFRIT--------SDRPL 487
            ..|.. ..:.|..|.|..|.        :||.|
 Worm   394 DILER-QQRMQKDLHLLHIAPYASKFPQNDRML 425

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	31/78 (40%)
		NR_LBD_RXR_like	237..480	CDD:132741	51/288 (18%)
nhr-141	NP_001023845.2	NR_DBD_HNF4A	43..119	CDD:143518	31/75 (41%)
		HOLI	249..399	CDD:214658	39/187 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158249
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840