Protein Alignment usp and nhr-173

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_509119.4
• Gene: nhr-173 / 183862
• WormBaseID: WBGene00016975
• Length: 508
• Species: Caenorhabditis elegans
• Alignment Length: 564
• Identity: 121/564 - (21%)
• Similarity: 204/564 - (36%)
• Gaps: 178/564 - (31%)

  Fly    48 MSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQ--------------------YP 92
            |:::|..|.......||   ...|...:|:::..|:..:.|||                    :|
 Worm     1 MNILHYSPTQTDQLFNN---FQYQNHTSPSNSTSSSEGSDQQQIVSDFVDTASFMISWNGLGEFP 62

  Fly    93 -----------PNHPLS----------GSKHL--------CSICGDRASGKHYGVYSCEGCKGFF 128
                       |...||          ...||        |::|||||:|.||.|.||.|||.||
 Worm    63 DTEEDIKHVIQPTENLSLNIEEQKEIVAFHHLPRNVCPTICAVCGDRATGYHYEVPSCNGCKTFF 127

  Fly   129 KRTVRKDLTYACRENRNC--IIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSA 191
            :|||.....|.|.....|  ::.|.:|..|:.||:|||:..||...|:|......: ||......
 Worm   128 RRTVLSQRKYECMRGGKCFNVLPKEKRCSCRSCRFQKCVEVGMNPFAIQTNDSLSS-NAVVTKIV 191

  Fly   192 SGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGD 256
            ....:|...|:..:|..                   ..:...:|.|.:|:|:|:.....|.:..|
 Worm   192 GKRKNSVDNSIPSTSKL-------------------TVLPEVISMDNAIDRLIDGLMYLEIKVDD 237

  Fly   257 -------------RALTFL-----------RVGPYSTVQPDYKGAVSALCQVVNKQ--------- 288
                         |:|.:.           ::||    .|::     .|.|:.:::
 Worm   238 FRSCAYNPPTHEYRSLKYHLEQQPMISMADKLGP----MPNW-----PLRQISHEEMKEYIESGN 293

  Fly   289 ---------------LFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGG 338
                           :...||||:......|:..:||::||:|..::|:..|.|:.|..:..|
 Worm   294 SEPMTPERKNWFVYDILTSVEYAKTFMFLHQIGKEDQILLLRAVVLKLMHLNQAFYSYENKYD-- 356

  Fly   339 AGGGGGGLGH-DGSF------ERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRILSELSVK 396
                  .:.| ||:.      :..:|.....|:...|.                .:.:..|.::.
 Worm   357 ------MIFHPDGTVPPHSWKKNENPNDSISQMMTKQK----------------MEEMKEEFTLS 399

  Fly   397 MKRL---NLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREK-VYA-CLDEHCRLEHPGDDG--R 454
            :::.   .||:||....|||.|.|..|.|:...|...:.||| .|: .|.::| |.:.|..|  .
 Worm   400 IRQFVTYQLDKREYVLFKAITLCNATISGLSDHAREVVTREKEKYSKALMKYC-LANRGMKGPAH 463

  Fly   455 FAQLLLRLPALRSISLKCQDHLFLFRITS--------DRPLEEL 490
            :|.::.....|.:.....:|..|:.::..        |..:||:
 Worm   464 YAAIIALSNGLENRQKNQKDFHFIMKMMKKGFKFDLVDDVMEEV 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	37/85 (44%)
		NR_LBD_RXR_like	237..480	CDD:132741	60/304 (20%)
nhr-173	NP_509119.4	NR_DBD_HNF4A	103..180	CDD:143518	35/76 (46%)
		HOLI	307..476	CDD:214658	45/193 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158256
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840