Protein Alignment usp and nhr-129

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001122887.1
• Gene: nhr-129 / 183635
• WormBaseID: WBGene00003719
• Length: 420
• Species: Caenorhabditis elegans
• Alignment Length: 410
• Identity: 85/410 - (20%)
• Similarity: 143/410 - (34%)
• Gaps: 116/410 - (28%)

  Fly   104 CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRN---RCQYCRYQKCL 165
            |.:||..|||.||.|.:|.|||.||:|.|.....:.|:.|.:| .|...|:   :|:.||..||.
 Worm    30 CFVCGGSASGYHYDVPACNGCKTFFRRYVISKRLFTCKLNDDC-FDLSTRDVPVKCRACRINKCF 93

  Fly   166 TCGMKREAVQEERQRG--ARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDD 228
            ..||...|::.::...  .:....|.:..|..:.                           ....
 Worm    94 AVGMNPHALEVDKTNTDCLKEVTKRKNMIGNDAV---------------------------NEKQ 131

  Fly   229 FMTNSV-SRDFSIERIIEAEQRAETQCGD-------------RALTFL-----------RVGPY- 267
            .:.||: |.:..|::|.:.....|.:...             |.|.|:           :.||.
 Worm   132 LVLNSLESMENKIQKIADMLTYLELKLDQFRASSYNPHWAEVRGLEFVLNSTNRISLADKFGPMP 196

  Fly   268 ------STVQPDYKGAVSALCQVVNK--------------QLFQMVEYARMMPHFAQVPLDDQVI 312
                  :.:.|.....:|....|:..              .:...:|||:....|.::...||:|
 Worm   197 GWPLLDNNLSPSRPPPLSHEKLVIGGPPPYSPKKKHWLYFNMLATIEYAKTFMFFHELLPRDQLI 261

  Fly   313 LLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGH-DGSFERRSPGLQPQQLFLNQSFSYHRNS 376
            |::...:..:...|::.|:....|...        | ||:.          |:..||.: |..|
 Worm   262 LIRYTTLACVNLLVSFSSVSKKYDTAV--------HPDGTL----------QMHRNQEY-YSSN- 306

  Fly   377 AIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMC--REKVYAC 439
                 |.:|         :.:.|..:.:.|...||||.|.||.:..:...|::.:.  |:|....
 Worm   307 -----VMSI---------IPLIRYQVQQIEYVLLKAICLCNPAVPDLSKHAQLLLAEERQKYSEA 357

  Fly   440 LDEHCRLEHPGDDGRFAQLL 459
            |.:||.........||..|:
 Worm   358 LLDHCIRNIGNGPSRFTDLI 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	30/76 (39%)
		NR_LBD_RXR_like	237..480	CDD:132741	50/271 (18%)
nhr-129	NP_001122887.1	ZnF_C4	30..99	CDD:197701	29/69 (42%)
		HOLI	236..386	CDD:214658	39/176 (22%)