Protein Alignment usp and nhr-260

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_503435.1
• Gene: nhr-260 / 183304
• WormBaseID: WBGene00016517
• Length: 398
• Species: Caenorhabditis elegans
• Alignment Length: 469
• Identity: 109/469 - (23%)
• Similarity: 170/469 - (36%)
• Gaps: 149/469 - (31%)

  Fly    43 PFMQAMSMVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHL---C 104
            ||...:.||              ::.||.:  .|::|..|:::          |.|..|.|   |
 Worm     3 PFEMHLDMV--------------TSEDALL--LPSTATPSSSS----------PSSIPKCLTERC 41

  Fly   105 SICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGM 169
            .:|.||::...||..:|.||..||:|.|...:.|.|...:.|:|....|..|:|||:||||..||
 Worm    42 KVCEDRSNNSRYGAPACLGCTVFFRRAVVNKMQYRCLREQKCLISFTYRCACRYCRFQKCLNVGM 106

  Fly   170 KREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSV 234
            :..::|.....|.|..:|.
 Worm   107 RPNSIQRRDLVGPRKLSGD---------------------------------------------- 125

  Fly   235 SRDFSIERIIEAEQRAETQCGDRA----LTFLRVGPY-STVQPD------------YKGAVSA-- 280
                |:..:|..|.:.||...:.|    ..|....|| |..|.|            ::....|
 Worm   126 ----SLPDVIVLEDQYETFLEEFASFQKKQFSEHLPYFSEHQVDVAFHKDQSNIVKFRRRARAHD 186

  Fly   281 ------LCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIA-NVAWCSIVSLDDGG 338
                  ||      |.|..|:...:..|.::|:|.:    |:...|..:| |:       :|.|.
 Worm   187 VNIMLKLC------LKQASEWGSRLKPFKKLPVDSK----KSMMAEYCLAFNL-------IDQGY 234

  Fly   339 AGGGGGGLG----HDGSFERRSPGLQPQQLF-LNQSFSYHRNSAIKAGVSAIF-DRILSELSVKM 397
            .......||    .:|||      :.|...| ||.:.....:..:|..:...| ..:::.|....
 Worm   235 KTSKEADLGIWLLQNGSF------MHPDYFFGLNVTNVNMESMKLKTQLHHNFVTEMINCLGTPF 293

  Fly   398 KRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYA-----CLDE---HCRLEHPGDDG- 453
            :||.:|..|.:.||.|:|..|..    ::..|...:|.|.|     |.:|   ||..:.| :.|
 Worm   294 RRLQIDDVECAALKIILLLTPSC----TKRAIYAGQEGVLAGLYTKCTEELMDHCMSKFP-ESGA 353

  Fly   454 -RFAQLLLRLPALR 466
             ||.::||.|..:|
 Worm   354 ERFGEILLLLGGIR 367

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	30/78 (38%)
		NR_LBD_RXR_like	237..480	CDD:132741	64/272 (24%)
nhr-260	NP_503435.1	NR_DBD_HNF4A	41..115	CDD:143518	29/73 (40%)
		HOLI	191..368	CDD:214658	51/205 (25%)