Protein Alignment usp and nhr-91

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001024953.1
• Gene: nhr-91 / 181621
• WormBaseID: WBGene00003681
• Length: 474
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 129/507 - (25%)
• Similarity: 205/507 - (40%)
• Gaps: 135/507 - (26%)

  Fly    10 FRLSHIKEEVKPDIS-QLNDSNNSSFSPKAESPVPFMQAMSMVHVLPGSNSASSNNNSAGDA--- 70
            |.|:|:...:.|.:. .:.||...||| :.|||                ||.:.::.||.:.
 Worm    30 FYLTHLASTLVPPMKLDMRDSMTPSFS-QTESP----------------NSETDDSTSAANKVLF 77

  Fly    71 QMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKRTVRKD 135
            .:...|.:...|.|.:           ..|..|||:|||:::|.|||..:||||||||||:|:..
 Worm    78 SILGTPTTDSTSNAVS-----------KSSSKLCSVCGDKSTGLHYGAATCEGCKGFFKRSVQNK 131

  Fly   136 LTYACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSASGGGSSGPG 200
            ..|.|.::..|.|||:.|||||.||::||::.||..|||:|:|..|.||
 Worm   132 KVYHCSQDNCCEIDKQNRNRCQSCRFRKCISKGMLTEAVREDRMPGGRN---------------- 180

  Fly   201 SVGGSSSQGGGGGGGVSGGMGSGNG----SDDFMTNSVSRDF----SIERIIEAEQRAETQCGDR 257
                        |..:.........    :.|::.....|.|    |.:::|  ::..|..|.||
 Worm   181 ------------GNSIYSNYKQRRSIIRKTKDYVEEQERRPFQSLPSGKKLI--KELVEMDCLDR 231

  Fly   258 ALTF--LRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIE 320
            .:..  ||:.|  :...|...|...|.::.::.:.|:||:.:.:|.|.::|::....||...|.|
 Worm   232 LINLKGLRINP--SANCDIAPACKRLTRIGDEIVEQLVEWTKTLPFFDELPVEAHTHLLTQRWAE 294

  Fly   321 LLIANVAW--CSIVSLDDGGAGGGGGGLGHDGSFERRSPG-------------LQPQQLFLNQSF 370
            |::.:..:  ||:.:.|                    ||.             ..||   :|...
 Worm   295 LVLLSAGYYACSVFTPD--------------------SPDTTEMIDETDEISFTNPQ---VNLRL 336

  Fly   371 SYHRNSAIKAGVSAIFDRILSELSVKMKR----------LNLDRRELSCLKAIILYNPDIRGIKS 425
            ..:|.|.: .|.....:.:..|....:.|          |.:......|:|||.|.:........
 Worm   337 LQNRLSLV-LGKEIPLEHVAKEAGPLVTRFTTLLHSFSNLKVSPEAYVCIKAITLLHLSADSTLD 400

  Fly   426 RAEIEMCREKVYACLDEHCR-----LEHPGDDGR---FAQLLLRLPALRSIS 469
            |:.|    :||....|...:     |..||:|.:   .||:|..||.||:.|
 Worm   401 RSII----DKVNTLQDHFVKTLQIHLHQPGEDAQTTSLAQILDWLPDLRNAS 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	42/75 (56%)
		NR_LBD_RXR_like	237..480	CDD:132741	60/272 (22%)
nhr-91	NP_001024953.1	NR_DBD_DHR4_like	92..181	CDD:143542	47/127 (37%)
		NR_LBD_DHR4_like	222..465	CDD:132751	57/257 (22%)