Protein Alignment usp and nhr-116

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_507273.2
• Gene: nhr-116 / 180129
• WormBaseID: WBGene00003706
• Length: 448
• Species: Caenorhabditis elegans
• Alignment Length: 506
• Identity: 106/506 - (20%)
• Similarity: 174/506 - (34%)
• Gaps: 154/506 - (30%)

  Fly    50 MVHVLPGSNSASSNNNSAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSK----HLCSICGDR 110
            |:|    |..::|.:......:.:.:|     .|.:|......|:....||:    ..|.:||..
 Worm     1 MIH----SRCSTSTDEPVDLPEFSLSP-----PALSAEPSTSSPSKKSIGSRVERPTECLVCGRS 56

  Fly   111 ASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCI-IDKRQR-NRCQYCRYQKCLTCGM---- 169
            |.|.||.|.||.|||.||:|......:::|:.:|:|. :.||:. .:|:.||.|:||:.||
 Worm    57 AHGYHYNVASCNGCKTFFRRMCLSGRSFSCKLDRDCFDLTKRKTPAKCRACRLQRCLSVGMDPGA 121

  Fly   170 -----------------KREAVQEERQRGARNAAGRLSASGGGSSGPGSVGGS------------ 205
                             ||..|:||.|...:    .::.....|..|..:..|
 Worm   122 MEVDEKAASSSTYKSLLKRSKVKEEDQDDCQ----IIALVSNNSKKPWELVKSLENKLQNTIDML 182

  Fly   206 ---SSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFS----IERIIEAEQRAETQCGDRALTFL- 262
               .|:                 .:.|..:|.:.|::    :|.:::.|.|         :.|.
 Worm   183 VYLESK-----------------VEKFRKSSYNPDWNEMDGLEFLLKTESR---------IGFAD 221

  Fly   263 RVGPYSTV-------------------------QPDYKGAVSALCQVVNKQLFQMVEYARMMPHF 302
            |.||....                         .||.|       |.:...||..||||:....|
 Worm   222 RYGPMKECPIRSDQKKLPPPPHPSSAKFGGPKHNPDRK-------QWMYFNLFTTVEYAKTFMFF 279

  Fly   303 AQVPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLN 367
            .::...|:.||.|...:..:..::::.|:....:......|      .||..|:     |..:.:
 Worm   280 HRLDSRDKFILTKHITLSCMNLHLSYISVARKSEVLTNPDG------TSFPSRT-----QAHYTS 333

  Fly   368 QSFSYHRNSAIKAGVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAE--IE 430
            ::.|.                      ..:.|..:...|.:.||||.|.||.:..:...|:  :.
 Worm   334 KTMSV----------------------APLIRYQIQYIEYTLLKAICLCNPAVPDLSHHAQEILS 376

  Fly   431 MCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRI 481
            ..|||....|.::|..........||||:.....|.. ..|.|..|.|..|
 Worm   377 KEREKYADALFDYCLRTRNDGPSHFAQLMQIFDVLER-QQKLQKDLHLLYI 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	33/98 (34%)
		NR_LBD_RXR_like	237..480	CDD:132741	54/274 (20%)
nhr-116	NP_507273.2	ZnF_C4	50..119	CDD:197701	29/68 (43%)
		HOLI	262..414	CDD:214658	38/185 (21%)