Protein Alignment usp and nhr-49

DIOPT Version :9

• Sequence 1: NP_001259168.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001367039.1
• Gene: nhr-49 / 172839
• WormBaseID: WBGene00003639
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 468
• Identity: 130/468 - (27%)
• Similarity: 204/468 - (43%)
• Gaps: 118/468 - (25%)

  Fly    97 LSGSKHL-----------------------CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTY 138
            |..|||:                       |::|||:::|.||||.||.||||||:|||.:|..:
 Worm     5 LDASKHIQLNQIDEESSDDFMDLVDPLAEPCAVCGDKSTGTHYGVISCNGCKGFFRRTVLRDQKF 69

  Fly   139 ACRENRNCIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAAGRLSASGGGS-----SG 198
            .||.|:.|:|||..|..|:|||:|||:..||||||:|.||.......:|   ||..|:     ..
 Worm    70 TCRFNKRCVIDKNFRCACRYCRFQKCVQVGMKREAIQFERDPVGSPTSG---ASLNGTPFKKDRS 131

  Fly   199 PGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAEQRAETQCGDRALTFLR 263
            ||...|:|:..|      |.|||..|......::||     |:.::|.|.|...:..:|   :.|
 Worm   132 PGYENGNSNGVG------SNGMGQENMRTVPQSSSV-----IDALMEMEARVNQEMCNR---YRR 182

  Fly   264 V-----------GPYSTVQPDYKGAVSA-------------LCQVVNKQLFQMVEYARMMPHFAQ 304
            .           |..:.:|.......||             |.::....|..|||:|:.:..|..
 Worm   183 SQIFANGSGGSNGNDTDIQQGSDSGASAFAPPNRPCTTEVDLNEISRTTLLLMVEWAKTINPFMD 247

  Fly   305 VPLDDQVILLKAAWIELLIANVAWCSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQS 369
            :.::|::||||....:.||...|:                          |||......||.|..
 Worm   248 LSMEDKIILLKNYAPQHLILMPAF--------------------------RSPDTTRVCLFNNTY 286

  Fly   370 FSYHRNSAIKA----GVSAIFDRILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIE 430
            .:...|:.:..    ..|.|..|:|.|:...|::|.:..:|..||||:...:|:.:|:.:.::|
 Worm   287 MTRDNNTDLNGFAAFKTSNITPRVLDEIVWPMRQLQMREQEFVCLKALAFLHPEAKGLSNSSQI- 350

  Fly   431 MCRE-------KVYACLDEHCRLEHPGDDG--RFAQLLLRLPALRSISLKCQDHLFLFRITS--- 483
            |.|:       .:||.:     |:...||.  |:..:||..|||::::....:::.|.:...
 Worm   351 MIRDARNRVLKALYAFI-----LDQMPDDAPTRYGNILLLAPALKALTQLLIENMTLTKFFGLAE 410

  Fly   484 -DRPLEELFLEQL 495
             |..|.|..|:.:
 Worm   411 VDSLLSEFILDDI 423

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_001259168.1	NR_DBD_RXR	102..178	CDD:143514	44/98 (45%)
		NR_LBD_RXR_like	237..480	CDD:132741	61/279 (22%)
nhr-49	NP_001367039.1	NR_DBD_HNF4A	35..110	CDD:143518	44/74 (59%)
		HOLI	228..382	CDD:214658	44/185 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103349
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4818
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840