Protein Alignment usp and nr2c2

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: XP_012817160.1
• Gene: nr2c2 / 100038183
• XenbaseID: XB-GENE-482536
• Length: 596
• Species: Xenopus tropicalis
• Alignment Length: 491
• Identity: 138/491 - (28%)
• Similarity: 218/491 - (44%)
• Gaps: 135/491 - (27%)

  Fly   104 CSICGDRASGKHYGVYSCEGCKGFFKRTVRKDLTYACRENRNCIIDKRQRNRCQYCRYQKCLTCG 168
            |.:|||:|||:|||..|||||||||||:|||.|||:||.:::|:|:|..|||||:||.:|||..|
 Frog   116 CVVCGDKASGRHYGAVSCEGCKGFFKRSVRKSLTYSCRSSQDCVINKHHRNRCQFCRLKKCLEMG 180

  Fly   169 MKREAVQEERQRG--ARNAAGRLSAS-------------------------GGGSSG---PGSVG 203
            ||.|:||.||:..  .|..|...:||                         |...:|   ||.:.
 Frog   181 MKMESVQSERKPFDIQREKASNCAASTEKIYIRKDLRSPLIATPTFVSDKDGARQTGLLDPGVLV 245

  Fly   204 G---------------------SSSQGGGGG--------GGVSGGMGSGNGSD----DFMTNSVS 235
            .                     .:||||.|.        ..::..:.:|:.:|    |..::.::
 Frog   246 NIQQPLIREDGTVILSSDAKQTEASQGGLGTLANVVTSLANLTESLNNGDTADVHPEDQYSSEIT 310

  Fly   236 RDF-SIERIIEAEQRA---------ETQCG--------DRALTFLRV-GP------------YST 269
            |.| ::.:.:...:.:         :...|        |:|...|.| ||            ..:
 Frog   311 RAFDTLAKALNTTEGSPVHNLADGIDASTGGNIHIISRDQATPILEVEGPLLSDTHVTFKLTMPS 375

  Fly   270 VQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPLDDQVILLKAAWIELLIANVAWCS-IVS 333
            ..|:|.. |..:|:..::.||..:.:||.:|.|..:..|....|::|.|.||....:|.|| ::|
 Frog   376 PMPEYLN-VHYICESASRLLFLSMHWARSIPAFQALGQDCNTNLVRACWNELFTLGLAQCSQVMS 439

  Fly   334 LDDGGAGGGGGGLGHDGSFERRSPGLQPQQLFLNQSFSYHRNSAIKAGVSAIFDRI--------- 389
            |                            ...|....::.:||..:..:|.  |||
 Frog   440 L----------------------------STILAAIVNHLQNSIQEDKLSG--DRIKQVMEHIWK 474

  Fly   390 LSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEIEMCREKVYACLDEHCRLEHPGDDGR 454
            |.|....|.:|.:|..|.:.|||::|::||..|:.|.|:||..:||....|.::.:..:|.|..|
 Frog   475 LQEFCNSMTKLGIDGYEYAYLKAVVLFSPDHPGLSSTAQIEKFQEKAQMELQDYVQKTYPDDTYR 539

  Fly   455 FAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEEL 490
            .|::|:||||||.:|....:.||...:..:.|::.:
 Frog   540 LARILVRLPALRLMSSNITEELFFTGLIGNVPIDSI 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	48/73 (66%)
		NR_LBD_RXR_like	237..480	CDD:132741	70/283 (25%)
nr2c2	XP_012817160.1	NR_DBD_TR2_like	111..197	CDD:143525	50/80 (63%)
		NR_LBD_TR2_like	361..582	CDD:132750	63/246 (26%)