Protein Alignment usp and nr2e3

DIOPT Version :10

• Sequence 1: NP_476781.1
• Gene: usp / 31165
• FlyBaseID: FBgn0003964
• Length: 508
• Species: Drosophila melanogaster
• Sequence 2: NP_001090633.1
• Gene: nr2e3 / 100036597
• XenbaseID: XB-GENE-485801
• Length: 404
• Species: Xenopus tropicalis
• Alignment Length: 457
• Identity: 140/457 - (30%)
• Similarity: 212/457 - (46%)
• Gaps: 89/457 - (19%)

  Fly    66 SAGDAQMAQAPNSAGGSAAAAVQQQYPPNHPLSGSKHLCSICGDRASGKHYGVYSCEGCKGFFKR 130
            |..|:|  ..|:.|.|.|         ||..|     ||.:|||.:||||||:::|.||.|||||
 Frog    10 STEDSQ--SVPSPAPGPA---------PNPHL-----LCRVCGDSSSGKHYGIFACNGCSGFFKR 58

  Fly   131 TVRKDLTYACRENRN-CIIDKRQRNRCQYCRYQKCLTCGMKREAVQEERQRGARNAA-------- 186
            :||:.|.|.|:.... |.:||..||:||.||.:|||..||.::|||.|||  .|:.|
 Frog    59 SVRRKLIYRCQAGTGLCPVDKAHRNQCQACRLKKCLQTGMNKDAVQNERQ--PRSTAQIRLDSID 121

  Fly   187 ----GRLSASGGGSSGPGSVGGSSSQGGGGGGGVSGGMGSGNGSDDFMTNSVSRDFSIERIIEAE 247
                .|..........|.|....::........:||.: |...:..||.:.::.:...:  :|.|
 Frog   122 LDTDSRSEHLATTRDPPPSCPQGNNLRTPIPSAISGTL-SPPHNHRFMASLMTAETCAK--LEPE 183

  Fly   248 QRAE-----TQCGDRALTFLRVGPYSTVQPDYKGAVSALCQVVNKQLFQMVEYARMMPHFAQVPL 307
            :..|     :...:|..|..::..:.|..|:.....||      :.|...|::|:.:|.|:.:|.
 Frog   184 EADENIDVTSNEPERTPTDFQISGFPTSSPEGVYETSA------RLLLMAVKWAKNLPVFSNLPF 242

  Fly   308 DDQVILLKAAWIEL-LIANVAW------CSIVSLDDGGAGGGGGGLGHDGSFERRSPGLQPQQLF 365
            .||||||:.||.|| |:..:.|      |.::|:.|
 Frog   243 RDQVILLEEAWSELFLLCAIQWSMPLDSCPLLSVPD----------------------------- 278

  Fly   366 LNQSFSYHRNSAIKAGVSAIFD-RILSELSVKMKRLNLDRRELSCLKAIILYNPDIRGIKSRAEI 429
              .|...|..|     ||:..| |||.|...:.|.||:|..|.:||||::|:.|:.||:|...:|
 Frog   279 --LSSQVHGKS-----VSSTIDVRILQETISRFKSLNVDPTEFACLKAVLLFKPETRGLKDPEQI 336

  Fly   430 EMCREKVYACLDEHCRLEHPGDDGRFAQLLLRLPALRSISLKCQDHLFLFRITSDRPLEELFLEQ 494
            |..:::....|.:|.|.::|....||.:|||..|:||.||.:..:.||..|...:.|:|:|..:.
 Frog   337 ENLQDQSQMMLAQHTRNQYPAQPVRFGKLLLLSPSLRFISSERIELLFFHRTIGNTPMEKLLCDM 401

  Fly   495 LE 496
            .:
 Frog   402 FK 403

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
usp	NP_476781.1	NR_DBD_RXR	102..178	CDD:143514	41/76 (54%)
		NR_LBD_RXR_like	237..480	CDD:132741	72/255 (28%)
nr2e3	NP_001090633.1	NR_DBD_PNR	24..115	CDD:143528	50/106 (47%)
		NR_LBD_Tlx_PNR_like	186..391	CDD:132748	71/246 (29%)