Protein Alignment Hr4 and Nr5a2

DIOPT Version :9

• Sequence 1: NP_001259161.1
• Gene: Hr4 / 31162
• FlyBaseID: FBgn0264562
• Length: 2123
• Species: Drosophila melanogaster
• Sequence 2: NP_068510.1
• Gene: Nr5a2 / 60349
• RGDID: 68353
• Length: 560
• Species: Rattus norvegicus
• Alignment Length: 769
• Identity: 182/769 - (23%)
• Similarity: 271/769 - (35%)
• Gaps: 288/769 - (37%)

  Fly   788 SPSAGSLTPSSSSGGGSVSGGGVGGPLTPSSVAPQNNEEAAQLLLSLGQTRIQDMRSRPHPFRTP 852
            :|:.||.||.|                  ..:..::.|:.|.|         .|...||.|.|:
  Rat    22 APAPGSETPHS------------------PKLEEKHREKRAGL---------PDRHRRPIPARS- 58

  Fly   853 HALNMERLWAGDYSQLPPGQLQALNLSAQQQQWGSSNSTGLGGVGGGMGGRNLEAPHEPTDEDEQ 917
                  ||     ..||..:.:|..|.....:.|.        :...|.....:..:...|||.:
  Rat    59 ------RL-----VMLPKVETEASGLVRSHGEQGQ--------MPENMQVSQFKMVNYSYDEDLE 104

  Fly   918 PLVCMICEDKATGLHYGIITCEGCKGFFKRTVQNRRVYTCVADGTCEITKAQRNRCQYCRFKKCI 982
            .| |.:|.||.:|.|||::|||.|||||||||||::.|||:.:..|:|.|.||.||.||||||||
  Rat   105 EL-CPVCGDKVSGYHYGLLTCESCKGFFKRTVQNQKRYTCIENQNCQIDKTQRKRCPYCRFKKCI 168

  Fly   983 EQGMVLQAVREDRMPGGRNS-GAVYNLYKVKYKKHKKTNQKQQQQAAQQQQQQAAAQQQHQQQQQ 1046
            :.||.|:|||.|||.||||. |.:|                 ::..|.:||::|..:....:.:.
  Rat   169 DVGMKLEAVRADRMRGGRNKFGPMY-----------------KRDRALKQQKKALIRANGLKLEA 216

  Fly  1047 HQQHQQHQQQQLHSPLHHHHHQGHQSHHAQQQHHPQLSPHHLLSPQQQQLAAAVAAAAQHQQQQQ 1111
            ..|..|.....|.|.:        |:.|:..:..| || |..|.|..
  Rat   217 MSQVIQAMPSDLTSAI--------QNIHSASKGLP-LS-HVALPPTD------------------ 253

  Fly  1112 QQQQQQQQAKLMGGVVDMKPMFLGPALKPELLQAPPMHSPAQQQQQQQQQQQQQQASPHLSLSSP 1176
                           .|..|....|                                  :|::.|
  Rat   254 ---------------YDRSPFVTSP----------------------------------ISMTMP 269

  Fly  1177 HQQQQQQQGQHQNHHQQQGGGGGGAGGGAQLPPHLVNGTILKTALTNPSEIVHLRHRLDSAVSSS 1241
                     .|.:.|..|..|            |..|..| |:...:|             .|||
  Rat   270 ---------PHGSLHGYQPYG------------HFPNRAI-KSEYPDP-------------YSSS 299

  Fly  1242 KDRQISYEHALGMIQTLIDCDAMEDIATLPH-FSEFLE---DKSEISEK---------------- 1286
            .:..:.|.:..| .||       ...|::|| ..|.|:   |:.::..|
  Rat   300 PESMMGYSYMDG-YQT-------SSPASIPHLILELLKCEPDEPQVQAKIMAYLQQEQNNRNRQE 356

  Fly  1287 -------LCNIGDSIVHKLVSWTKKLPFYLEIPVEIHTKLLTDKWHEILILTTAAYQALHGKRRG 1344
                   ||.:.|..:..:|.|.:...|:.|:.|:...|||.:.|.|:|||.....|..|||
  Rat   357 KLSAFGLLCKMADQTLFSIVEWARSSIFFRELKVDDQMKLLQNCWSELLILDHIYRQVAHGK--- 418

  Fly  1345 EGGGSRHGSPASTPLSTPTGTPLSTPIPSPAQPLHKDDPEFVSEV----NSHLSTLQTCLTTLMG 1405
            ||           .:...||.             |.|....:|..    |:.||..|
  Rat   419 EG-----------TIFLVTGE-------------HVDYSSIISNTEVAFNNLLSLAQ-------- 451

  Fly  1406 QPIAMEQLKLDVGHMVDKMTQITIMFRRIKLKMEEYVCLKVYILLNKAEVE-------LESIQER 1463
                                ::.:..|.::....|:|||| :::|..::|:       :|.:||:
  Rat   452 --------------------ELVVRLRSLQFDQREFVCLK-FLVLFSSDVKNLENFQLVEGVQEQ 495

  Fly  1464 YVQVLRSYLQNSSPQNPQARLSELLSHIPEIQAAASLLLESKMFY------VPF 1511
            ....|..|...:.||..: :..:||..:|||: |.|...|..::|      ||:
  Rat   496 VNAALLDYTLCNYPQQTE-KFGQLLLRLPEIR-AISKQAEDYLYYKHVNGDVPY 547

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr4	NP_001259161.1	NR_DBD_DHR4_like	913..1002	CDD:143542	56/88 (64%)
		NR_LBD_DHR4_like	1256..1515	CDD:132751	66/300 (22%)
Nr5a2	NP_068510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	17..54		11/58 (19%)
		NR_DBD_Lrh-1_like	107..199	CDD:143541	55/108 (51%)
		FTZ-F1 box. /evidence=ECO:0000250	176..205		15/45 (33%)
		NR_LBD_Lrh-1	320..560	CDD:132754	63/286 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920