Protein Alignment Hr4 and nr6a1b

DIOPT Version :9

• Sequence 1: NP_001259161.1
• Gene: Hr4 / 31162
• FlyBaseID: FBgn0264562
• Length: 2123
• Species: Drosophila melanogaster
• Sequence 2: NP_001028892.1
• Gene: nr6a1b / 497167
• ZFINID: ZDB-GENE-040724-202
• Length: 455
• Species: Danio rerio
• Alignment Length: 610
• Identity: 143/610 - (23%)
• Similarity: 228/610 - (37%)
• Gaps: 231/610 - (37%)

  Fly   921 CMICEDKATGLHYGIITCEGCKGFFKRTVQNRRVYTCVADGTCEITKAQRNRCQYCRFKKCIEQG 985
            |:||.|:|:|||||||:||||||||||::.|:|:|.|..|..|::::.|||||||||.:||::.|
Zfish    41 CLICGDRASGLHYGIISCEGCKGFFKRSICNKRIYRCNRDKNCQMSRKQRNRCQYCRLQKCLQMG 105

  Fly   986 MVLQAVREDRMPGGRNS--GAVYNLYKVKYKKHKKTNQKQQQQAAQQQQQQAAAQQQHQQQQQHQ 1048
            |..:|:|||.||||||.  |.|                                   |...::.:
Zfish   106 MNRKAIREDGMPGGRNKMIGPV-----------------------------------HISLEEIE 135

  Fly  1049 QHQQHQQQQLHSPLHHHHHQGHQSHHAQQQHHPQLSPHHLLSPQQQQLAAAVAAAAQHQQQQQQQ 1113
            :....|:.:..|.|......|:.:|.         ||.:.||...|.|:.:.:.:...:.:
Zfish   136 RLMSGQEFKEGSDLSDSWSHGYSNHS---------SPGNSLSEGGQSLSFSSSRSVSCRDE---- 187

  Fly  1114 QQQQQQAKLMGGVVDMKPMFLGPALKPELLQAPPMHSPAQQQQQQQQQQQQQQASPHLSLSSPHQ 1178
                                   .:.|:|                          .|..|...:
Zfish   188 -----------------------CISPQL--------------------------THTFLMCKY- 202

  Fly  1179 QQQQQQGQHQNHHQQQGGGGGGAGGGAQLPPHLVNGTILKTALTNPSEIVHLRHRLDSAVSSSKD 1243
                                       .|||  ..|:||||.          .|.|..
Zfish   203 ---------------------------PLPP--PTGSILKTQ----------THTLTG------- 221

  Fly  1244 RQISYEHALGMIQTLIDCDAMEDIA--TLPHFSE--FLEDKSEISEKLCNIGDSIVHKLVSWTKK 1304
                        |.|.|    ||:.  |.|...|  :...:||:...||.|.|.::.:.:.|.|:
Zfish   222 ------------QILAD----EDLTPLTTPMLIEDGYSVTQSELLALLCGIADELLFRQIVWLKR 270

  Fly  1305 LPFYLEIPVEIHTKLLTDKWHEILILTTAAYQALHGKRRGEGGGSRHGSPASTPLSTPTGTPLST 1369
            |||:.::.::..|:||...||::::|::...               |.:.....|:..|
Zfish   271 LPFFTDLSIKDCTRLLGSSWHQLILLSSITV---------------HSAQILGELANVT------ 314

  Fly  1370 PIPSPAQPLHKDDPEFVSEVNSHLSTLQTCLTTLMGQPIAMEQLKLDVGHMVDKMTQITIMFRR- 1433
                     |...|      :||  |||.     .|:. |||           .|..:..:||:
Zfish   315 ---------HHYTP------SSH--TLQR-----FGED-AME-----------VMESLNFLFRKF 345

  Fly  1434 --IKLKMEEYVCLKVYILLNKAEV------ELESIQERYVQVLRSYLQNSSPQNPQARLSELLSH 1490
              :.:..|||.|||...|||:...      .|:.:.|||..:.|...:...||.|: |.|::::.
Zfish   346 HQLNISNEEYSCLKTITLLNQETTGLCNTSMLKQLSERYWTLCRELTERLHPQRPK-RFSDIITC 409

  Fly  1491 IPEIQAAASLLLESKMFYVPFVLNS 1515
            :.||:..:..::...:..:|.:..:
Zfish   410 LTEIRHTSGKMMSIPLEQLPLLFKA 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr4	NP_001259161.1	NR_DBD_DHR4_like	913..1002	CDD:143542	50/80 (63%)
		NR_LBD_DHR4_like	1256..1515	CDD:132751	64/271 (24%)
nr6a1b	NP_001028892.1	NR_DBD_GCNF_like	33..122	CDD:143543	50/80 (63%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	145..173		8/36 (22%)
		NR_LBD_DHR4_like	222..434	CDD:132751	64/271 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595657
Domainoid	1	1.000	111	1.000	Domainoid score	I6197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_108526
Panther	1	1.100	-	-	O	PTHR48092
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4570
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.850