Protein Alignment Hr4 and nr5a1b

DIOPT Version :9

• Sequence 1: NP_001259161.1
• Gene: Hr4 / 31162
• FlyBaseID: FBgn0264562
• Length: 2123
• Species: Drosophila melanogaster
• Sequence 2: NP_997999.1
• Gene: nr5a1b / 405759
• ZFINID: ZDB-GENE-040702-6
• Length: 502
• Species: Danio rerio
• Alignment Length: 628
• Identity: 138/628 - (21%)
• Similarity: 222/628 - (35%)
• Gaps: 217/628 - (34%)

  Fly   920 VCMICEDKATGLHYGIITCEGCKGFFKRTVQNRRVYTCVADGTCEITKAQRNRCQYCRFKKCIEQ 984
            :|.:|.||.:|.|||::|||.|||||||||||.:.|||.....|:|.|.||.||.:|||:||:..
Zfish    12 MCPVCGDKVSGYHYGLLTCESCKGFFKRTVQNNKRYTCAESQDCKIDKTQRKRCPFCRFQKCLNV 76

  Fly   985 GMVLQAVREDRMPGGRNSGAVYNLYKVKYKKHKKTNQKQQQQA---AQQQQQQAAAQQQHQQQQQ 1046
            ||.|:|||.|||.||||.      :...||:.:..  |||::|   |...:.:|........|..
Zfish    77 GMRLEAVRADRMRGGRNK------FGPMYKRDRAL--KQQKKALIRASGLKMEATPPLLTSPQPD 133

  Fly  1047 H--------------------------QQHQQHQQQQL--------HSPLHHHHHQGHQSHHAQQ 1077
            :                          .:...:....|        |:||...:...:....|.:
Zfish   134 YTFSTALSVPAPKNTHPNIVTSVAPTDYERSLYASSSLSLSVPIPAHTPLPAQYPYPNLPSRAIK 198

  Fly  1078 QHHPQLSPHHLLSPQQQQLAAAVAAAAQHQQQQQQQQQQQQQAKLMGGVVDMKPMFLGPALKPEL 1142
            ..:|.    |..|.:....|::..:...:...:|.:.....|....|..|        |.|..|.
Zfish   199 SEYPD----HYTSSEHYTSASSPESVPGYTYIEQTRVSSSPQVVAPGLTV--------PPLVLEF 251

  Fly  1143 LQAPPMHSPAQQQQQQQQQQQQQQASPHLSLSSPHQQQQQQQGQHQNHHQQQGGGGGGAGGGAQL 1207
            ::.           :|.:.|.|.:.|.||:    |.||:|.......:.:|
Zfish   252 VRC-----------EQDELQVQSKISAHLA----HLQQEQNSRSTAANQEQ-------------- 287

  Fly  1208 PPHLVNGTILKTALTNPSEIVHLRHRLDSAVSSSKDRQISYEHALGMIQTLIDCDAMEDIATLPH 1272
                                        |:..::|..::|   ..|:
Zfish   288 ----------------------------SSRLAAKPERLS---TFGL------------------ 303

  Fly  1273 FSEFLEDKSEISEKLCNIGDSIVHKLVSWTKKLPFYLEIPVEIHTKLLTDKWHEILILTTAAYQA 1337
                          :|::.|..:..:|.|.:...|:.|:.|....|||.:.|.|:|:|...|.|.
Zfish   304 --------------MCHMADQTLFSIVEWARSCIFFKELKVGDQMKLLHNCWSELLVLDYVARQL 354

  Fly  1338 LHGKRRGEGGGSRHGSPASTPLSTPTGTPLSTPIPSPAQPLHKDDPEFVSEVNSHLSTLQTCLTT 1402
            .|||                                                       :..:..
Zfish   355 HHGK-------------------------------------------------------EDSVLL 364

  Fly  1403 LMGQPIAMEQLKLDVG----HMVDKMTQITIMFRRIKLKMEEYVCLKVYILLNKAEVEL------ 1457
            :.||.:.:..|....|    .|:.:..::....:.::|...|..||| |::|...:|:|
Zfish   365 ITGQEVELASLLAQAGVTLSGMIQRGQELVQRLQELQLDRRETACLK-YLILFNPDVKLLENQPY 428

  Fly  1458 -ESIQERYVQVLRSYLQNSSPQNPQARLSELLSHIPEIQAAAS 1499
             ||:.|:....|..|...:.||.|. |.|::|..:||::|.:|
Zfish   429 VESVYEQVNAALLEYTLCAYPQFPD-RFSQILLRLPELRALSS 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr4	NP_001259161.1	NR_DBD_DHR4_like	913..1002	CDD:143542	49/81 (60%)
		NR_LBD_DHR4_like	1256..1515	CDD:132751	48/255 (19%)
nr5a1b	NP_997999.1	NR_DBD_Lrh-1_like	13..105	CDD:143541	52/97 (54%)
		NR_LBD_Ftz-F1_like	244..498	CDD:132742	67/384 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920