Protein Alignment Hr4 and nhr-25

DIOPT Version :9

• Sequence 1: NP_001259161.1
• Gene: Hr4 / 31162
• FlyBaseID: FBgn0264562
• Length: 2123
• Species: Drosophila melanogaster
• Sequence 2: NP_001024550.1
• Gene: nhr-25 / 181432
• WormBaseID: WBGene00003623
• Length: 572
• Species: Caenorhabditis elegans
• Alignment Length: 477
• Identity: 120/477 - (25%)
• Similarity: 183/477 - (38%)
• Gaps: 130/477 - (27%)

  Fly   911 PTDEDEQPLVCMICEDKATGLHYGIITCEGCKGFFKRTVQNRRVYTCVADGTCEITKAQRNRCQY 975
            |..|.|   :|.:|.|:.:|.|||::|||.|||||||||||::.|.|.|:..|.:.:..|.||..
 Worm    11 PNHEGE---MCPVCGDRVSGYHYGLLTCESCKGFFKRTVQNKKQYQCSAEANCHVDRTCRKRCPS 72

  Fly   976 CRFKKCIEQGMVLQAVREDRMPGGRNS-GAVYNLYKVKYKKHK--------KTNQKQQQQAAQQQ 1031
            |||:||:..||.::|||.|||.||||. |:.|.    |.:.|:        .|.|......||.|
 Worm    73 CRFQKCLTMGMKMEAVRADRMRGGRNKFGSFYK----KDRAHRMQRNAMRVSTVQVPAVLGAQSQ 133

  Fly  1032 QQQAAAQQQHQ----QQQQHQQHQQHQQQQLHSPLHHHHHQGH-QSHHAQQQHHPQLS------- 1084
            .|......:||    ...|:.|.....|.::.:......:..| ||.......:.|||
 Worm   134 AQTFYQPPEHQVSSSTTDQNNQINYFDQTKIKTEYIKTEYDAHLQSPTLSSSTNQQLSVSDFIMR 198

  Fly  1085 PHHLLSPQQQQLAAAVAAAAQHQQQQQQQQQQQQQAKLMGGVVDMKPMFLGPALKPELLQAPPMH 1149
            |.:|:.|                        |...|.|:|..:|      .|.|:         |
 Worm   199 PGYLVDP------------------------QDSLAVLLGSTID------DPLLR---------H 224

  Fly  1150 S-PAQQQQQQQQQQQQQQASPHLSLSSPHQQQQQQQGQHQNHHQQQGGGGGGAGGGAQLPPHLVN 1213
            : ||..|..:.:|:....:               :|..|.:.|              ..|.:..|
 Worm   225 TFPAAYQLNEVKQEPFDYS---------------EQFIHHSLH--------------DYPTYTSN 260

  Fly  1214 GTILKTALTNPSEIVHLRHRLDSAVSSSKDRQISYEHALGMIQTLIDCDAMEDIATLPHF----- 1273
            .|...|.:  |...|.....|.::.||:...:::...:...|..|  |.|..: .|:.||
 Worm   261 TTNYATMM--PMTTVSSTQSLVTSTSSTTTGRMTEASSTSPILPL--CPAPTE-KTVDHFYNSSI 320

  Fly  1274 ---SEFLEDKSEISEKLCNI-GDSIVHK--------------LVSWTKKLPFYLEIPVEIHTKLL 1320
               .:.|.|.::|:....:: |.|...|              :|.|.|....:.::.::....||
 Worm   321 AEMCKTLPDDAQIARIFTSVKGTSKPEKHAFSIQVAEENLKDIVIWAKNDQLFSKLSLDDQMILL 385

  Fly  1321 TDKWHEILI--LTTAAYQALHG 1340
            ...|..:.|  :|.|   .:||
 Worm   386 QTSWTTVHIVDITNA---MVHG 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hr4	NP_001259161.1	NR_DBD_DHR4_like	913..1002	CDD:143542	46/88 (52%)
		NR_LBD_DHR4_like	1256..1515	CDD:132751	23/110 (21%)
nhr-25	NP_001024550.1	NR_DBD_Lrh-1_like	18..110	CDD:143541	48/95 (51%)
		NR_LBD_F2	349..501	CDD:132728	11/59 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D278717at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920