DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3587 and kti12

DIOPT Version :9

Sequence 1:	NP_569965.1	Gene:	CG3587 / 31160	FlyBaseID:	FBgn0023521	Length:	299	Species:	Drosophila melanogaster
Sequence 2:	NP_001119890.1	Gene:	kti12 / 751662	ZFINID:	ZDB-GENE-060825-174	Length:	275	Species:	Danio rerio

Alignment Length:	296	Identity:	120/296 - (40%)
Similarity:	183/296 - (61%)	Gaps:	28/296 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPLVVITGLPASGKSTRARQLRDHFVER-GRKVHLISENEAVPKAGFGKNSHTGDSQKEKVVRSD 64
            |||:::.|.|.|||:.||::|||:|.:. |||||::.:.:    .|..|||...||||||.:|..
Zfish     1 MPLILMCGYPCSGKTRRAQELRDYFTQNTGRKVHIVGDED----QGIDKNSVYADSQKEKNLRGA 61

  Fly    65 LKSEASRHLNQEDLVILDAGNYIKGYRYELYCMSKVSRTTQCTVFTCIPQEEAWTFNSQRTAPDE 129
            |::|..|.:|::|:||||:.||||||||||:|:.|.::|..|.|::....:.:..:|..|.|
Zfish    62 LRAEVERKVNKDDIVILDSLNYIKGYRYELFCLIKHTQTPHCLVYSLTSADLSSEWNKDREA--- 123

  Fly   130 LPGDSERVQPVDNSDVPYTRETFDALCQRYEEPQSNNRWDSPLVVVLPKDTLDMEAIYKALYESQ 194
                          |..||:|..|||..|:|.|.|.|||||||..:...|:|..|||..||::.:
Zfish   124 --------------DSQYTQEILDALILRFEAPDSRNRWDSPLFTIQQDDSLPFEAICDALFKRK 174

  Fly   195 PLPPNQSTYNAPLGTTNYLFELDKIVQAIIKEILGAVKIKAFGQL-RIPGSRNPVKVATSMNALQ 258
            ..||||||.:.||.:||:|:||||:.|.::..:|.:.|....|.| .|||:...:::..|:|.::
Zfish   175 APPPNQSTKSQPLSSTNFLYELDKVTQDVLMAVLESQKTSVPGDLISIPGATEKIELTRSLNMVE 239

  Fly   259 LNRLRQKFITSTCHASQTSPTP-LEQVPHLFVQFIN 293
            |.:||::||:.|    :..||. :.|:.::|||::|
Zfish   240 LRKLRRQFISYT----KMHPTENIGQIANMFVQYLN 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3587	NP_569965.1	KTI12	3..293	CDD:285611	117/292 (40%)
CG3587	NP_569965.1	NK	3..263	CDD:302627	106/261 (41%)
kti12	NP_001119890.1	KTI12	3..271	CDD:285611	117/292 (40%)
kti12	NP_001119890.1	NK	3..271	CDD:302627	117/292 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595026
Domainoid	1	1.000	220	1.000	Domainoid score	I2550
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6347
Inparanoid	1	1.050	220	1.000	Inparanoid score	I3530
OMA	1	1.010	-	-		QHG55163
OrthoDB	1	1.010	-	-		D1300128at2759
OrthoFinder	1	1.000	-	-		FOG0005231
OrthoInspector	1	1.000	-	-		oto40458
orthoMCL	1	0.900	-	-		OOG6_103506
Panther	1	1.100	-	-	LDO	PTHR12435
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R646
SonicParanoid	1	1.000	-	-		X3752
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940