Protein Alignment Ocrl and Synj1

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_038944618.1
• Gene: Synj1 / 85238
• RGDID: 69434
• Length: 1609
• Species: Rattus norvegicus
• Alignment Length: 588
• Identity: 159/588 - (27%)
• Similarity: 252/588 - (42%)
• Gaps: 136/588 - (23%)

  Fly   178 EYIVYKDIIIYCATWNVNN----KTCSDSNNPLRAWLACS-------------EKPPDIYAIGLQ 225
            :|...|.|.:...|||||.    ::.:..|..|..||..:             .||.||:|||.:
  Rat   569 KYSKPKKIRVCVGTWNVNGGKQFRSIAFKNQTLTDWLLDAPKLAGIQEFQDKRSKPTDIFAIGFE 633

  Fly   226 EL-DTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRC 289
            |: :.....::|::...  :|.|..::..::..|.:|.:|.|.:||...|.|.:|.|....|...
  Rat   634 EMVELNAGNIVNASTTN--QKLWAVELQKTISRDNKYVLLASEQLVGVCLFVFIRPQHAPFIRDV 696

  Fly   290 RPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFDDGRT 354
            ...:|..|:....||||.|||.:..:..::|||.||.||....|:|||:|:..|...:.|..||.
  Rat   697 AVDTVKTGMGGATGNKGAVAIRMLFHTTSLCFVCSHFAAGQSQVKERNEDFVEIARKLSFPMGRM 761

  Fly   355 ISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFR 419
            :..||::||.||.||||..|  .:....|...|.::.|:..|||..:...|:.|.|:.||::.|.
  Rat   762 LFSHDYVFWCGDFNYRIDLP--NEEVKELIRQQNWDSLIAGDQLINQKNAGQIFRGFLEGKVTFA 824

  Fly   420 PTYKYDPGTDNYDSSEKQRAPAYCDRVLWK--------------------------------GTR 452
            ||||||..:::||:|||.|.||:.|||||:                                ||
  Rat   825 PTYKYDLFSEDYDTSEKCRTPAWTDRVLWRRRKWPFDRSAEDLDLLNASFQDESKILYTWTPGT- 888

  Fly   453 IEQLAYNSIMEIRQSDHKPVYA-----VFQVKVKTRDEVKYKRVQEEVLKAVDKRENDNQPQINV 512
               |.:....|::.|||:||.|     :|:|:.:.|.:: ||    ||:..      ...|.
  Rat   889 ---LLHYGRAELKTSDHRPVVALIDIDIFEVEAEERQKI-YK----EVIAV------QGPPD--- 936

  Fly   513 EKTVIDFGTVRFNEPSTRDFNVYNNCPLPVDFSFKEKDIHAICEPWLHVDPRQDSLLIDSARSIR 577
                   |||..:..|:...|.:          |.:..|..:.:.:.|..   :.:||   |.:.
  Rat   937 -------GTVLVSIKSSAQENTF----------FDDALIDELLQQFAHFG---EVILI---RFVE 978

  Fly   578 LKMNANVRTIAGLLRKIRASDNFDILILHVENGRDIF---ITVT---GDY------QPSCFGLSM 630
            .||         .:..:..|...::|.|   ||:::.   ||:|   .|:      :.|...:|:
  Rat   979 DKM---------WVTFLEGSSALNVLSL---NGKELLNRTITITLKSPDWIKTLEEEMSLEKISV 1031

  Fly   631 ETMCRTDRPL----SEYSQD-QIKQLMNDESPEYRVTMPREFFLLIDYLYRQGSKQVGAFPSYDS 690
            .....|...|    :|.|.| .::..::|.|.|....:|:       :|....|..:|..||...
  Rat  1032 TLPSSTSSTLLGEDAEVSADFDMEGDVDDYSAEVEELLPQ-------HLQPSSSSGLGTSPSSSP 1089

  Fly   691 RLS 693
            |.|
  Rat  1090 RTS 1092

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268
		INPP5c_INPP5B	185..478	CDD:197327	110/347 (32%)
		RhoGAP_OCRL1	614..823	CDD:239845	22/97 (23%)
Synj1	XP_038944618.1	COG5329	100..523	CDD:227637
		INPP5c_Synj1	576..911	CDD:197332	109/342 (32%)
		RRM_SF	910..1052	CDD:473069	36/190 (19%)
		PHA03247	<1097..1498	CDD:223021