DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and AT1G71710

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_565023.1	Gene:	AT1G71710 / 843501	AraportID:	AT1G71710	Length:	664	Species:	Arabidopsis thaliana

Alignment Length:	508	Identity:	142/508 - (27%)
Similarity:	228/508 - (44%)	Gaps:	97/508 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 TKDIVKER--FKEDETIEYIFEAYQIKGPEYSNRLLALVSSQSGGTFAIIAFSYLRTPLSSANEL 82
            |.||::|.  |:.|............:..|.::||.||  ...||....:  ..|..|.:....:
plant   224 THDIIEEEVAFESDSDAGVEIHPIDEEEEEETDRLWAL--KHDGGVIGEV--KTLVDPNTGLPVV 284

  Fly    83 IINKVFAI----DHNFQLRQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVAKVISFKS 143
            .|.:.|:|    |....||.||...|:    |..:.:.|              .:.:.:::|.|.
plant   285 EIKRQFSIPKKLDRQLCLRADSFKGIS----DDDSTQTG--------------MKTINRMLSGKE 331

  Fly   144 TMAQHDPETVLNFRW---LNDYRQIGEVKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNP 205
            .:....||..||...   |:....|..|| .||..:| :..|...           |:.:.:||.
plant   332 RIGLSWPEPPLNMLGPCVLDRQPSIKTVK-SLKTAKS-FKAYSSF-----------KSVAGNNNG 383

  Fly   206 LRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEILMSHRLV 270
            :         ||::.|  |.|:|  .|.::...:..|                  |..|:|.::|
plant   384 I---------PPEVLA--LAEMD--LKLLMERKRRPA------------------YVRLVSKQMV 417

  Fly   271 ATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEE 335
            ..:||:.|::.||:||...|..:|..|:...:||||.|::|:.:|:...||:|:||.|....|::
plant   418 GILLTIWVKRSLRKHIQNVRVSTVGVGVMGYIGNKGAVSVSMSINQTFFCFINTHLTAGEREVDQ 482

  Fly   336 --RNQDYNAIVEGIRFDD------GRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELL 392
              ||.|.:.|.:...|..      .:.|.||:.|.|:||||||:..  ..::...|...:.:..|
plant   483 IKRNADVHEIHKRTVFHSVSALGLPKLIYDHERIIWLGDLNYRLSS--SYEKTRDLISKREWSKL 545

  Fly   393 LQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNY---DSSEKQRAPAYCDRVLWKGTRIE 454
            |:||||.:|.|:|:.|:|::||.:.|.|||||...:|.|   |....:|.||:|||||..|..:.
plant   546 LEYDQLVKEYRKGRAFDGWSEGTLHFPPTYKYQANSDEYTANDGKAPKRTPAWCDRVLSYGKGMR 610

  Fly   455 QLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKR--------VQEEVLKAV 499
            .:.|.. .|.:.|||:||.|::..:|:.....|.:|        :::|.|.||
plant   611 LVHYRR-TEQKFSDHRPVTAIYMAEVEVFSARKLQRALTFTDAEIEDEGLVAV 662

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622	31/148 (21%)
		INPP5c_INPP5B	185..478	CDD:197327	95/303 (31%)
		RhoGAP_OCRL1	614..823	CDD:239845
AT1G71710	NP_565023.1	EEP	10..652	CDD:382041	138/496 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1399831at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2994
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X494
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820