Protein Alignment Ocrl and FRA3

DIOPT Version :9

• Sequence 1: NP_001259153.1
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_176736.2
• Gene: FRA3 / 842869
• AraportID: AT1G65580
• Length: 1101
• Species: Arabidopsis thaliana
• Alignment Length: 609
• Identity: 151/609 - (24%)
• Similarity: 246/609 - (40%)
• Gaps: 147/609 - (24%)

  Fly   168 VKQELKKRESEYIVYKDIIIYCATWNV-NNKTCSDSNNPLRAWLACSEKPPDIYAIGLQELDTPT 231
            ::.||..:|..|...:::.|...|||| ..:..:||   |.:||.|:....:|..:||||::...
plant   521 LRAELAGKEFLYSRIENLKILAGTWNVGEGRASTDS---LVSWLGCAATGVEIVVVGLQEVEMGA 582

  Fly   232 KAMLNSTQVQAIEKQ-------WIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRC 289
            ..:..|...:.:..:       |:|.:..::.....:..:.|.:|...::.|.||..|:.|:...
plant   583 GVLAMSAAKETVGLEGSPLGQWWLDMIGKTLDEGSSFVRVGSRQLAGLLICVWVRHDLKPHVGDV 647

  Fly   290 RPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDY-------------- 340
            ...:|..|....:||||.|.:.|::.:..:||||.|.|||:..|..||.|:
plant   648 DAAAVPCGFGRAIGNKGAVGVRLRMYDRVLCFVNCHFAAHLEAVNRRNADFDHVYRTMTFSRQSS 712

  Fly   341 --NAIVEGIRFDDGRT------------------ISDHDHIFWVGDLNYRIQEPPGQQRPGPLSD 385
              ||.|.|..|  |.|                  :|:.|.:.::||.|||:.:....:....:|.
plant   713 SLNAGVAGASF--GVTMPRGGNALGVNTIEARPELSEADMVIFLGDFNYRLDDITYDETRDFISQ 775

  Fly   386 AQTYELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYD---PGTDNYDSSEKQRAPAYCDRVL 447
             :.::.|.:.|||..||..|..|:|..|..|:|.||||::   .|...|||.||:|.||:|||:|
plant   776 -RCFDWLREKDQLHTEMEAGNVFQGMREAIIRFPPTYKFERHQAGLAGYDSGEKKRIPAWCDRIL 839

  Fly   448 WKGTR----------------IEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVL 496
            ::..:                |.|  |::.||:..||||||..||.||:...||
plant   840 YRDNKKHLGAECSLDCPVVSSISQ--YDACMEVTDSDHKPVRCVFSVKIARVDE----------- 891

  Fly   497 KAVDKRENDNQPQIN------------VEKTVIDFGTVRFNEPSTRDFNVYNNCPLPVDFSFKEK 549
             :|.::|..|....|            |.:|::....:......:....:.|.....:.| ||
plant   892 -SVRRQEYGNIINSNKKIKVLLGELSKVPETIVSTNNIILQNQDSTILRITNKSEKNIAF-FK-- 952

  Fly   550 DIHAICE-----------------------PWLHVDPRQDSLLIDSAR--SIRLKMNANVRT-IA 588
               .|||                       .||.|.|...::..:...  |:.|:....|.. :.
plant   953 ---IICEGQSKIEEDGQAHDHRARGSFGFPQWLEVSPGTGTIKPNQIAEVSVHLEDFPTVEEFVD 1014

  Fly   589 GLLRKIRASDNFD--ILILHVENGRDIFITVT------------GDYQPSCFGLSMET------M 633
            |:.:.....|..|  ::::.|.:||  |.|.|            |....:.|....:|      :
plant  1015 GVAQNSWCEDTRDKEVILVLVVHGR--FSTETRKHRIRVRHCPRGGPAKNHFNDGTKTSGQINAL 1077

  Fly   634 CRTDRPLSEYSQDQIKQLMNDESP 657
            .|:|......:.|.::||.|..||
plant  1078 HRSDYHQLSNTLDVVEQLKNLHSP 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	103/353 (29%)
		RhoGAP_OCRL1	614..823	CDD:239845	14/62 (23%)
FRA3	NP_176736.2	WD40	182..510	CDD:421866
		WD40 repeat	186..221	CDD:293791
		WD40 repeat	230..264	CDD:293791
		WD40 repeat	413..442	CDD:293791
		WD40 repeat	449..481	CDD:293791
		INPP5c	538..884	CDD:197308	103/353 (29%)
		Motile_Sperm	919..1043	CDD:421531	22/131 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101357
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.670