DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and IP5PII

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_567547.1	Gene:	IP5PII / 827526	AraportID:	AT4G18010	Length:	646	Species:	Arabidopsis thaliana

Alignment Length:	484	Identity:	141/484 - (29%)
Similarity:	227/484 - (46%)	Gaps:	72/484 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EAYQIKGPEYSNRLLALVSSQSGGTFAIIAFSYLRTPLSSANELIINKV---FAIDHNFQLRQDS 100
            |:...:.|..:|.  ||..|.|..:..|:|        ..||.:|.:.:   ...||:..|..:.
plant   185 ESVYDQSPSCNNN--ALHRSHSAPSSPILA--------QEANSIISHVMVENLVADHSLDLATNE 239

  Fly   101 KSSITTQQFDLSTAEDGPIKYYYYATESHHY----EEFVAKVISFKSTMAQHDPETVLN-FRWLN 160
            .....|....|....:..:.:...|.:|:..    |..:.:|.|..:|:....||.... .|:.:
plant   240 FIDAATALPSLEPQRNPNMDWPELALDSNPQIVGSEGKLRRVFSSNATLGFKLPENPSGASRFAS 304

  Fly   161 DYRQIGEVKQELKKRESEYIVYKDIIIYCATWN-----VNNKTCSDSNNPLRAWLACSEKPPDIY 220
            :.||:        ||...:....      .:||     ::|::.|.|.         :|:...|.
plant   305 EARQL--------KRSRSFETLN------LSWNDIKEEIDNRSSSSSE---------AEEAAKIM 346

  Fly   221 AIGLQELDTPTKAMLNSTQVQ---AIEKQWID---KMMDSVHPDVEYEILMSHRLVATMLTVIVR 279
            .....:.|:.::...:..:::   .:.:..::   |:.||    .:|..::|.::|...::|.:|
plant   347 HDDSSDGDSSSQDEEDGDKIRNSYGLPEDLVEECRKVKDS----QKYVRIVSKQMVGIYVSVWIR 407

  Fly   280 KQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHL-AAHM-GYVEERNQDYNA 342
            ::||:|:...:...|..|:...:||||.|:||:.|.:..:|||.||| :.|. |..:.||.|...
plant   408 RRLRRHVNNLKVSPVGVGLMGYMGNKGSVSISMTLYQSRMCFVCSHLTSGHKDGAEQRRNADVYE 472

  Fly   343 IVEGIRF------DDGRTISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQE 401
            |:...||      |..|||..||.:||.||||||:....|:.|  .|...:.::.|...|||.:|
plant   473 IIRRTRFASVLDTDQPRTIPCHDQVFWFGDLNYRLNMSDGEVR--KLVSQKRWDELKNSDQLIRE 535

  Fly   402 MRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSS-----EKQRAPAYCDRVLWKGTRIEQLAYNSI 461
            :|||..|:|:.||.|||.|||||:..:|.|...     ||:||||:|||:||.|..|.|..|..
plant   536 LRRGHVFDGWREGPIKFPPTYKYEFDSDRYAGENLREPEKKRAPAWCDRILWLGKGIRQECYKR- 599

  Fly   462 MEIRQSDHKPVYAVFQVKVKTRDEVKYKR 490
            .|||.|||:||.::|.|.|:..|..|.:|
plant   600 SEIRMSDHRPVTSIFNVGVEVFDHRKLQR 628

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622	26/131 (20%)
		INPP5c_INPP5B	185..478	CDD:197327	106/316 (34%)
		RhoGAP_OCRL1	614..823	CDD:239845
IP5PII	NP_567547.1	PLN03191	1..646	CDD:215624	141/484 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	193	1.000	Domainoid score	I922
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1399831at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2994
orthoMCL	1	0.900	-	-		OOG6_101357
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X494
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720