DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and 5PTase14

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_001189651.1	Gene:	5PTase14 / 817740	AraportID:	AT2G31830	Length:	1173	Species:	Arabidopsis thaliana

Alignment Length:	486	Identity:	130/486 - (26%)
Similarity:	219/486 - (45%)	Gaps:	80/486 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   168 VKQELKKRESEYIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKPPDIYAIGLQELDTPTK 232
            ::.||.::|..|.....:.|...||||.....  |...|.:||..:.....|.||||||:|....
plant   563 IRTELSQKEMAYARQDSVKILIGTWNVGEGRA--SRGALVSWLGSAVSDVGIVAIGLQEVDMGAG 625

  Fly   233 AMLNST-------QVQAIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLRQHIIRCR 290
            .:..||       :..|:.:.|:|.:.:::.....:|.:.|.:|...::::.|||.:|.|:....
plant   626 FLAMSTAKETVGVEGSAVGQWWLDAIGNALDERNTFERMGSRQLAGLLISLWVRKSIRTHVGDLD 690

  Fly   291 PKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIRFDDGRTI 355
            ..:|..|....:||||||.:.:::.:..:||||.|||||:..|..||.|:|.|...:.|..|:::
plant   691 VAAVPCGFGRAIGNKGGVGLRIRVYDRIMCFVNCHLAAHLEAVTRRNADFNHIYRSMVFSKGQSV 755

  Fly   356 --------------------------------SDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQT 388
                                            :..|.:.:.||.|||:......:....:|. ::
plant   756 YTAAAAGASTSAQALKNNPNTNNSTEEEKSHLASADLVAFFGDFNYRLFGITYDEARDFISH-RS 819

  Fly   389 YELLLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYD---PGTDNYDSSEKQRAPAYCDRVLWKG 450
            ::.|.:.|||||||..||.|:|..|..|.|.||||::   ||...|||.||:|.||:||||:::.
plant   820 FDWLREKDQLRQEMNEGKVFQGMREALITFPPTYKFEKNKPGLGGYDSGEKKRIPAWCDRVIYRD 884

  Fly   451 TR--------------IEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVDK 501
            .:              ...:.|.:.|::.:||||||.......:...|:...::...:::|:.:|
plant   885 NQSISYTECSLKCPVVSSTIMYEACMDVTESDHKPVRCKLHANIAHTDKSVRRQELGKIVKSNEK 949

  Fly   502 -----RENDNQPQINV---------EKTVIDFGTVRFNEPSTRD-FNVYNNCPLPVDFSFKEKDI 551
                 .|..:.|:.:|         :.|.|  .|:|....|:|. ||:.......|....:|.|.
plant   950 LRAMFEELKSVPETSVSTNNILLHSQDTFI--FTIRNTSNSSRAIFNIVCKGQTLVREDGEEPDN 1012

  Fly   552 HAI----CEPWLHVDPRQDSLLIDSARSIRL 578
            |:.    ...||.|.|....:..|::..:::
plant  1013 HSRGTFGLPRWLEVSPGAGIIKPDASLQVKV 1043

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	103/348 (30%)
		RhoGAP_OCRL1	614..823	CDD:239845
5PTase14	NP_001189651.1	WD40	218..551	CDD:295369
		WD40	<218..384	CDD:225201
		WD40 repeat	451..484	CDD:293791
		WD40 repeat	490..523	CDD:293791
		WD40 repeat	529..565	CDD:293791	0/1 (0%)
		INPP5c	580..926	CDD:197308	103/348 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101357
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.670