Protein Alignment Ocrl and inpp5e

DIOPT Version :9

• Sequence 1: NP_001259153.1
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_001096089.2
• Gene: inpp5e / 606579
• ZFINID: ZDB-GENE-050809-23
• Length: 635
• Species: Danio rerio
• Alignment Length: 475
• Identity: 130/475 - (27%)
• Similarity: 211/475 - (44%)
• Gaps: 90/475 - (18%)

  Fly    94 FQLRQDSKSSI---TTQQFDLSTAEDGPI-------KYYYYATESHHYEEFVA---KVISFKSTM 145
            :.|.::|.:|.   ||.:.|....:.|.:       :.:...::|...:..|:   .|.|.|||.
Zfish   183 YPLLENSTASASLRTTNRIDRDCLDYGVVGRRGRSERLHRNLSDSRLLDTMVSDNTSVHSMKSTY 247

  Fly   146 AQHD---PETVLNFRWLNDYRQIGEV--------KQELKKRESEYIVYKDIIIYCATWNVNNKTC 199
            :..:   |..|.|..:|.     |.|        .:||.:    |...:.:.||.||||:..:..
Zfish   248 SVLNPIRPRDVRNRSFLE-----GSVLGNGALLGAEELDR----YFPERRLGIYIATWNMQGEKG 303

  Fly   200 SDSNNPLRAWLACSEKPPDIYAIGLQELDTPTKAMLNSTQVQAIEKQWIDKMMDSVHPDVEYEIL 264
            ...|.........::...|:|.||:|| ..|.:            ::|..::.:::.|   |.::
Zfish   304 LPYNLDDLLLPTDTDFAQDVYVIGVQE-GCPDR------------REWEIRLQETLGP---YYVM 352

  Fly   265 M---SHRLVATMLTVIVRKQLRQHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHL 326
            :   :|.::  .|||.||:.|..........:|...|.:.:..||.|.|.......:..||.||.
Zfish   353 LYAAAHGVL--YLTVFVRRDLIWFCSEVEHATVTTRIISQIKTKGAVGIGFTFFGTSFLFVTSHF 415

  Fly   327 AAHMGYVEERNQDYNAIVEGIRFDDG--------RTISD----HDHIFWVGDLNYRIQEPPGQQR 379
            .:....|.||..|||.|:|.:.....        .|.||    .|.:||.||.|:|:.:..|...
Zfish   416 TSGDSKVYERILDYNKIIEALALPRNLPDTNPYRSTTSDVTTRFDEVFWFGDFNFRLNKARGDVE 480

  Fly   380 PGPLSDAQTYEL--LLQYDQLRQEMRRGKCFEGYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAY 442
             ..|:.....::  |||:|||.:||:.|..|:|:.|..|.|.||||:|.|.|.||::.|||.|:|
Zfish   481 -AILNQGVGVDMSPLLQHDQLTREMKEGSIFKGFQEASIHFPPTYKFDIGCDVYDTTTKQRTPSY 544

  Fly   443 CDRVLWKGTR---IEQLAYNSIMEIRQSDHKPVYAVFQVKVKT-RDEVKY--------------- 488
            .||:|::..:   |..:.|.|...|:.|||:||..:||||::. ||.:..
Zfish   545 TDRILYRNRQADDIRVIKYTSCSSIKTSDHRPVIGMFQVKLRPGRDNIPLGAGLFDRSLYLEGIR 609

  Fly   489 KRVQEEVLK--AVDKRENDN 506
            :|:..|:.|  ||.|.:|::
Zfish   610 RRITRELKKREAVMKNQNNS 629

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622	18/84 (21%)
		INPP5c_INPP5B	185..478	CDD:197327	95/312 (30%)
		RhoGAP_OCRL1	614..823	CDD:239845
inpp5e	NP_001096089.2	INPP5c_INPP5E-like	285..583	CDD:197329	95/316 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910