Protein Alignment Ocrl and inpp5kb

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: XP_005155332.2
• Gene: inpp5kb / 566188
• ZFINID: ZDB-GENE-100408-3
• Length: 526
• Species: Danio rerio
• Alignment Length: 571
• Identity: 138/571 - (24%)
• Similarity: 238/571 - (41%)
• Gaps: 135/571 - (23%)

  Fly    95 QLRQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVAKVISFKSTMAQHDPETVLNFRWL 159
            ::|.||.|::|:|    ||:                     |:.| .:..:||       ....|
Zfish     9 RMRSDSMSTMTSQ----STS---------------------ARFI-LRQRLAQ-------LLTCL 40

  Fly   160 NDYRQIGEVKQELKKRESE-------YIVYKDIIIYCATWNVNNKTCSDSNNPLRAWLACSEKP- 216
            .|.....|..:|:.:...|       |...:...::..||||..   ::....:|:.|....:|
Zfish    41 EDLSSDDEANEEVSRTLDEAFNLCGRYSNRESFRLHMVTWNVGT---AEPPADVRSLLQLDSQPT 102

  Fly   217 PDIYAIGLQELDTPTKAMLNSTQVQ-----AIEKQWIDKMMDSVHPDVEYEILMSHRLVATMLTV 276
            .|:|.|||||        :|:|.|:     .:|..|...:|:::.|: .|..:.|.|:.. :|.:
Zfish   103 TDLYVIGLQE--------VNATPVRYISDLIVEDTWSHLLMETLAPE-GYIKVTSVRMQG-LLLI 157

  Fly   277 IVRKQLRQHIIRCRPKSVAR-GIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDY 340
            :..||:....||....:..| |:|...|||||:::........:||:|.||||||.|..:|..::
Zfish   158 LFAKQVHLPFIRDIQSTYTRTGLFGYWGNKGGISVRFSFYGEMLCFLNCHLAAHMNYALQRMDEF 222

  Fly   341 NAIVEGIRFDDGRT--ISDHDHIFWVGDLNYRIQEPPGQQRPGPLSDAQTYELLLQYDQLRQEMR 403
            ..|::...||...|  :.||..:||.||||:||.:.........::::: :.||...|||....:
Zfish   223 EYILDTQEFDMFNTPQVLDHKVVFWFGDLNFRIADHGMHFLRSSINNSR-FNLLWDRDQLSMLKK 286

  Fly   404 RGKCFEGYTEGEIKFRPTYKYDPGTDNYDS---------SEKQRAPAYCDRVLW----KGTRIE- 454
            :....:.:.||.::|:||||:|..::.||:         :.|:|.||:.||:||    |.|.||
Zfish   287 KEPILQEFEEGPLRFKPTYKFDRFSETYDTRAPRTWFGLTGKKRKPAWTDRILWRIKPKATEIED 351

  Fly   455 -------------------QLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVD 500
                               |..|...:....||||||...|.::::.:.|.....:..|.:.:.|
Zfish   352 EKSSTASSADDDEFSVKVTQDMYTCDVSYGVSDHKPVIGTFNLEMRKKVETPLVALTVEGIWSAD 416

  Fly   501 KRENDNQPQI-NVEKTVIDF-GTVRFNEPSTRDFNVYNNCPLPVDFSFKEKDIHAICEPWLHVDP 563
            :........: |.|.:..|: |..:....|..|::.:                     .|:
Zfish   417 EDAIFTYTILENFESSTFDWIGLYKIGFKSASDYSTF---------------------AWV---- 456

  Fly   564 RQDSLLIDSARSIRLKMNAN-VRTIAG----------LLRKIRASDNFDIL 603
             :|..:..:...:.::||.| :..:||          :...|..|.||.||
Zfish   457 -KDDEVAANGEVVMVQMNKNELPLLAGDYVLGYFSTNMQTLIAFSPNFQIL 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	12/64 (19%)
		INPP5c_INPP5B	185..478	CDD:197327	98/334 (29%)
		RhoGAP_OCRL1	614..823	CDD:239845
inpp5kb	XP_005155332.2	INPP5c_INPP5J-like	73..394	CDD:197328	98/334 (29%)
		SKICH	405..505	CDD:465482	19/125 (15%)