DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ocrl and Sh2d1b2

DIOPT Version :9

Sequence 1:	NP_001259153.1	Gene:	Ocrl / 31157	FlyBaseID:	FBgn0023508	Length:	850	Species:	Drosophila melanogaster
Sequence 2:	NP_001028671.1	Gene:	Sh2d1b2 / 545378	MGIID:	3622649	Length:	132	Species:	Mus musculus

Alignment Length:	134	Identity:	29/134 - (21%)
Similarity:	46/134 - (34%)	Gaps:	57/134 - (42%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 GTD-NYDSSEKQRAP-AYCDRVLWKGTRIEQLAYNSIMEIRQSDHKPVYAVFQVKVKTRDEVKYK 489
            |.| |:...:.:..| |.|..|.:|     :|.||             |.:|      |::..|.
Mouse    23 GVDGNFLIRDSESVPGALCLCVSFK-----KLVYN-------------YRIF------REKNGYY 63

  Fly   490 RVQEEVLKAVDKRENDNQPQI---NVEKTVIDFGT------VRFNEPSTR------------DFN 533
            |::.|          .:.|:.   |:|:.:..|.|      |..:.|..|            :.|
Mouse    64 RIETE----------PSTPKTIFPNLEELISKFKTPGQGMVVHLSNPIMRSGFCPGARRLNLEAN 118

  Fly   534 VYNN 537
            ||.|
Mouse   119 VYEN 122

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_001259153.1	PH-like	23..163	CDD:302622
		INPP5c_INPP5B	185..478	CDD:197327	13/52 (25%)
		RhoGAP_OCRL1	614..823	CDD:239845
Sh2d1b2	NP_001028671.1	SH2_SAP1	1..103	CDD:198205	24/113 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900