Protein Alignment Ocrl and Synj

DIOPT Version :10

• Sequence 1: NP_569962.2
• Gene: Ocrl / 31157
• FlyBaseID: FBgn0023508
• Length: 850
• Species: Drosophila melanogaster
• Sequence 2: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 171/632 - (27%)
• Similarity: 261/632 - (41%)
• Gaps: 182/632 - (28%)

  Fly    76 LSSANELIINKVF----AIDHNFQLRQDSKSSITTQQFDLSTAEDGPIKYYYYATESHHYEEFVA 136
            :::.||  ::|::    ||....:|...::|:..|.|.:|                ..:.::...
  Fly   443 INNGNE--VSKIYAGTGAIQGGSKLMDGARSAARTIQNNL----------------LDNSKQEAI 489

  Fly   137 KVISFKSTMAQ---------------HDPETVLNFRWLNDYRQIGEVKQELKKRESEYIVYKDII 186
            .|:...||::.               |.|.|||               :||.||.:||:..:...
  Fly   490 DVLLVGSTLSSELADRARILLPSNMLHAPTTVL---------------RELCKRYTEYVRPRMAR 539

  Fly   187 IYCATWNVN--------------------------NKTCSDSNNPLRAWLACSEK---PPDIYAI 222
            :...|:|||                          :|...|.|||       ||.   |.|||||
  Fly   540 VAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNNP-------SENVDHPVDIYAI 597

  Fly   223 GLQELDTPTKAMLNSTQVQAIE----KQWIDKMMDSVHPDVEYEILMSHRLVATMLTVIVRKQLR 283
            |.:|:     ..||::.:.|..    |.|.:::..::..|.:|.:|...:||...|.:.:|.:..
  Fly   598 GFEEI-----VDLNASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHA 657

  Fly   284 QHIIRCRPKSVARGIFNTLGNKGGVAISLQLNEGNICFVNSHLAAHMGYVEERNQDYNAIVEGIR 348
            .||.......|..|:....||||..||...|:..::|||.:|.||....|.|||.||..|...:.
  Fly   658 PHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLA 722

  Fly   349 FDDGRTISDHDHIFWVGDLNYRIQEPPGQ----QRPGPLSDAQTYELLLQYDQLRQEMRRGKCFE 409
            |..|||:..||.:||.||.||||.....:    .|.|.||      .:|::||||:|...|..|.
  Fly   723 FPMGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNGDLS------TVLEFDQLRKEQEAGNVFG 781

  Fly   410 GYTEGEIKFRPTYKYDPGTDNYDSSEKQRAPAYCDRVLWKGTRI-------------EQLAYNSI 461
            .:.||||.|.||||||..:|:||:||||||||:.|||||:..:.             .:|.:...
  Fly   782 EFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKLIHYGR 846

  Fly   462 MEIRQSDHKPVYAVFQVKVKTRDEVKYKRVQEEVLKAVDKRE--------------NDNQPQI-- 510
            .|::||||:||.|:...::...|:.:.:.|.|:|::.:...:              :::.|.|
  Fly   847 SELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLESSATGDEDGPTIYD 911

  Fly   511 -NV------------EKTVIDF-----------GTVRFNEPSTRDFNVYNNCPLPVDFSFKEKDI 551
             ||            |.|::.:           |....|..|.:...|   |.|.:....|.||
  Fly   912 ENVMSALITELSKMGEVTLVRYVEDTMWVTFRDGESALNASSKKSIQV---CGLDLILELKSKD- 972

  Fly   552 HAICEPWLHVDPRQDSLLIDSARSI----RLKMNANVRTIAGLLRKI 594
                  |.|        |:||...:    .:.:.||....|.||:.|
  Fly   973 ------WQH--------LVDSEIELCTTNTIPLCANPVEHAQLLQAI 1005

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ocrl	NP_569962.2	INPP5B_PH	23..160	CDD:465268	18/102 (18%)
		INPP5c_INPP5B	185..478	CDD:197327	117/342 (34%)
		RhoGAP_OCRL1	614..823	CDD:239845
Synj	NP_569729.1	COG5329	61..493	CDD:227637	11/67 (16%)
		INPP5c_Synj	538..863	CDD:197323	117/342 (34%)
		DUF1866	862..1008	CDD:286093	30/162 (19%)